Large-scale long-term follow-up study of Japanese patients with non-alcoholic Fatty liver disease for the onset of hepatocellular carcinoma
…, Y Arase, K Ikeda, Y Seko, N Imai… - Official journal of the …, 2012 - journals.lww.com
OBJECTIVES: The aim of this study was to determine the incidence and risk factors of
hepatocellular carcinoma (HCC), and to elucidate the utility of two non-invasive predictive …
hepatocellular carcinoma (HCC), and to elucidate the utility of two non-invasive predictive …
A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes
…, M Reiterer, N Montoya-Oviedo, EA Homan, N Imai… - Nature cell …, 2023 - nature.com
The pancreatic islets are composed of discrete hormone-producing cells that orchestrate
systemic glucose homeostasis. Here we identify subsets of beta cells using a single-cell …
systemic glucose homeostasis. Here we identify subsets of beta cells using a single-cell …
[HTML][HTML] Transarterial chemoembolization for hepatocellular carcinoma: A review of techniques
N Imai, M Ishigami, Y Ishizu, T Kuzuya… - World journal of …, 2014 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is one of the most common malignant diseases worldwide.
While curative therapies, including resection, liver transplantation, and percutaneous …
While curative therapies, including resection, liver transplantation, and percutaneous …
Difference in malignancies of chronic liver disease due to non‐alcoholic fatty liver disease or hepatitis C in Japanese elderly patients
…, Y Suzuki, Y Kawamura, N Akuta, N Imai… - Hepatology …, 2012 - Wiley Online Library
Aim: Malignancies that include hepatocellular carcinoma often occurred in patients with
chronic liver disease. The aim of this retrospective match control study was to assess the …
chronic liver disease. The aim of this retrospective match control study was to assess the …
[HTML][HTML] Patients with low muscle mass have characteristic microbiome with low potential for amino acid synthesis in chronic liver disease
K Yamamoto, Y Ishizu, T Honda, T Ito, N Imai… - Scientific Reports, 2022 - nature.com
Sarcopenia is thought to be related to the microbiome, but not enough reports in chronic
liver disease (CLD) patients. In addition to the differences in microbiome, the role of the …
liver disease (CLD) patients. In addition to the differences in microbiome, the role of the …
Clinical course of liver injury induced by immune checkpoint inhibitors in patients with advanced malignancies
…, T Yamamoto, K Mizuno, K Yamamoto, N Imai… - Hepatology …, 2021 - Springer
Background The clinical course of liver injury induced by immune checkpoint inhibitors (ICIs)
varies among individuals, and there were few reports on the therapeutic effects of …
varies among individuals, and there were few reports on the therapeutic effects of …
[HTML][HTML] Nuclear Receptor CoRepressors, NCOR1 and SMRT, are required for maintaining systemic metabolic homeostasis
MJ Ritter, I Amano, N Imai, LS De Oliveira, KR Vella… - Molecular …, 2021 - Elsevier
Objective The nuclear receptor corepressor 1 (NCOR1) and the silencing mediator of retinoic
acid and thyroid hormone (SMRT, also known as NCOR2) play critical and specific roles in …
acid and thyroid hormone (SMRT, also known as NCOR2) play critical and specific roles in …
[HTML][HTML] Conditioned medium from stem cells derived from human exfoliated deciduous teeth ameliorates NASH via the Gut-Liver axis
…, T Ito, T Tanaka, S Yokoyama, K Yamamoto, N Imai… - Scientific reports, 2021 - nature.com
Non-alcoholic steatohepatitis (NASH) occurrence has been increasing and is becoming a
major cause of liver cirrhosis and liver cancer. However, effective treatments for NASH are still …
major cause of liver cirrhosis and liver cancer. However, effective treatments for NASH are still …
Development rate of chronic kidney disease in hepatitis C virus patients with advanced fibrosis after interferon therapy
…, H Sezaki, T Hosaka, K Ogawa, N Imai… - Hepatology …, 2011 - Wiley Online Library
… Imai et al. have reported that about 20% of the Japanese adult population have stage 3 to 5
CKD … Our results agreed with Imai's report in the fact that end-stage CKD patients were few. …
CKD … Our results agreed with Imai's report in the fact that end-stage CKD patients were few. …
Trimming the fat: acetyl‐CoA carboxylase inhibition for the management of NAFLD
N Imai, DE Cohen - Hepatology, 2018 - journals.lww.com
Abstract Treatment of chronic hepatitis B (CHB) patients with nucleos (t) ide analogs (NAs)
suppresses hepatitis B virus (HBV) DNA synthesis but does not affect synthesis of HBV …
suppresses hepatitis B virus (HBV) DNA synthesis but does not affect synthesis of HBV …