[HTML][HTML] SARS-CoV-2 evolution and spike-specific CD4+ T-cell response in persistent COVID-19 with severe HIV immune suppression

…, A Pérez-Gómez, P Gallego-García, N Estévez-Gómez… - Microorganisms, 2022 - mdpi.com
Intra-host evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has
been reported in cases with persistent coronavirus disease 2019 (COVID-19). In this study, …

[HTML][HTML] Clonality and timing of relapsing colorectal cancer metastasis revealed through whole-genome single-cell sequencing

…, L Tomás, M Valecha, N Estévez-Gómez… - Cancer letters, 2022 - Elsevier
Recurrence of tumor cells following local and systemic therapy is a significant hurdle in cancer.
Most patients with metastatic colorectal cancer (mCRC) will relapse, despite resection of …

[HTML][HTML] OmniSARS2: A highly sensitive and specific RT-qPCR-based COVID-19 diagnostic method designed to withstand SARS-CoV-2 lineage evolution

…, C Calçada, F Branca, N Estévez-Gómez… - Biomedicines, 2021 - mdpi.com
Extensive transmission of SARS-CoV-2 during the COVID-19 pandemic allowed the generation
of thousands of mutations within its genome. While several of these become rare, others …

Comparison of single-cell whole-genome amplification strategies

N Estévez-Gómez, T Prieto, A Guillaumet-Adkins… - BioRxiv, 2018 - biorxiv.org
Single-cell genomics is an alluring area that holds the potential to change the way we
understand cell populations. Due to the small amount of DNA within a single cell, whole-genome …

[HTML][HTML] Comparative analysis of capture methods for genomic profiling of circulating tumor cells in colorectal cancer

JM Alves, N Estévez-Gómez, M Valecha… - Genomics, 2022 - Elsevier
The genomic profiling of circulating tumor cells (CTCs) in the bloodstream should provide
clinically relevant information on therapeutic efficacy and help predict cancer survival. Here, …

Dispersal history of SARS-CoV-2 in Galicia, Spain

P Gallego-García, N Estévez-Gómez, L De Chiara… - medRxiv, 2024 - medrxiv.org
The dynamics of SARS-CoV-2 transmission are influenced by a variety of factors, including
social restrictions and the emergence of distinct variants. In this study, we delve into the …

Limited genomic reconstruction of SARS-CoV-2 transmission history within local epidemiological clusters

P Gallego-García, N Varela, N Estévez-Gómez… - Virus …, 2022 - academic.oup.com
A detailed understanding of how and when severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) transmission occurs is crucial for designing effective prevention measures. …

Dispersal history of SARS-CoV-2 in Galicia, Spain (preprint)

P Gallego-García, N Estévez-Gómez, L De Chiara… - 2024 - pesquisa.bvsalud.org
The dynamics of SARS-CoV-2 transmission are influenced by a variety of factors, including
social restrictions and the emergence of distinct variants. In this study, we delve into the …

Limited genomic reconstruction of SARS-CoV-2 transmission history within local epidemiological clusters (preprint)

P Gallego-García, N Varela, N Estévez-Gómez… - 2021 - pesquisa.bvsalud.org
A detailed understanding of how and when SARS-CoV-2 transmission occurs is crucial for
designing effective prevention measures. Other than contact tracing, genome sequencing …

[HTML][HTML] Whole-genome amplification of cancer and healthy human single cells

NE Gómez - 2018 - portalcientifico.uvigo.gal
1. Introducción La célula es la unidad básica de la vida. Los sistemas biológicos complejos
como los organismos multicelulares están organizados en grupos de células individuales, …