We have previously provided the first genetic evidence that angiotensin converting enzyme
2 (ACE2) is the critical receptor for severe acute respiratory syndrome coronavirus (SARS-…

In recent years considerable progress has been made in the development of faithful procedures
for the differentiation of human pluripotent stem cells (hPSCs). An important step in this …

A partir de los resultados de una investigación encaminada a la mejora de la calidad de
vida de las familias con un hijo o hija con discapacidad intelectual, el objetivo del presente …

Defined transcription factors can induce epigenetic reprogramming of adult mammalian
cells into induced pluripotent stem cells. Although DNA factors are integrated during some …

Angiotensin converting enzyme 2 (ACE2) is the crucial severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) receptor and protects multiple tissues, including the lung, from …

Mouse and human fibroblasts were the first cell types successfully reprogrammed by ectopic
expression of OCT4, SOX2, KLF4, and c-MYC (OSKM)(Lowry et al., 2008; Maherali et al., …

Reprogramming of pig somatic cells to induced pluripotent stem cells provides a tremendous
advance in the field of regenerative medicine since the pig represents an ideal large …

The International Society for Stem Cell Research has updated its Guidelines for Stem Cell
Research and Clinical Translation in order to address advances in stem cell science and …

This monograph, written by the pioneers of IVF and reproductive medicine, celebrates the
history, achievements, and medical advancements made over the last 40 years in this …

Nuclear-architecture defects have been shown to correlate with the manifestation of a number
of human diseases as well as ageing 1 , 2 , 3 , 4 . It is therefore plausible that diseases …