User profiles for O. Binda

Olivier Binda

Université Claude Bernard Lyon 1
Verified email at univ-lyon1.fr
Cited by 1567

On your histone mark, SET, methylate!

O Binda - Epigenetics, 2013 - Taylor & Francis
… Bua DJ, Binda O. The return of the INGs, histone mark sensors and phospholipid
signaling effectors. Curr Drug Targets 2009; 10:418 - 31; http://dx.doi.org/10.2174/…

[PDF][PDF] ING4 mediates crosstalk between histone H3 K4 trimethylation and H3 acetylation to attenuate cellular transformation

T Hung, O Binda, KS Champagne, AJ Kuo, K Johnson… - Molecular cell, 2009 - cell.com
Aberrations in chromatin dynamics play a fundamental role in tumorigenesis, yet relatively
little is known of the molecular mechanisms linking histone lysine methylation to neoplastic …

[PDF][PDF] Negative regulation of hypoxic responses via induced Reptin methylation

…, JH Kim, JY Kim, SB Seo, H Lee, O Binda, O Gozani… - Molecular cell, 2010 - cell.com
Lysine methylation within histones is crucial for transcriptional regulation and thus links
chromatin states to biological outcomes. Although recent studies have extended lysine …

[HTML][HTML] Post-translational modifications of the histone variant H2AZ

A Sevilla, O Binda - Stem cell research, 2014 - ncbi.nlm.nih.gov
Gene expression is regulated by complex coordinated processes, including chromatin
remodeling, post-translational modifications of histones, and incorporation of non-allelic histone …

Hypoxia-induced methylation of a pontin chromatin remodeling factor

…, SH Lee, JB Yoon, O Binda, O Gozani… - Proceedings of the …, 2011 - National Acad Sciences
… Indeed, G9a protein levels were increased in both HeLa and MCF7 cells exposed to 6 h
of hypoxia (1% O 2 ) whereas there was no change in the levels of Suv39h1; another histone …

[HTML][HTML] Promyelocytic leukemia (PML) nuclear bodies (NBs) induce latent/quiescent HSV-1 genomes chromatinization through a PML NB/Histone H3. 3/H3. 3 …

…, N Poccardi, A Rousseau, C Kleijwegt, O Binda… - PLoS …, 2018 - journals.plos.org
Herpes simplex virus 1 (HSV-1) latency establishment is tightly controlled by promyelocytic
leukemia (PML) nuclear bodies (NBs) (or ND10), although their exact contribution is still …

SETD6 monomethylates H2AZ on lysine 7 and is required for the maintenance of embryonic stem cell self-renewal

O Binda, A Sevilla, G LeRoy, IR Lemischka… - Epigenetics, 2013 - Taylor & Francis
The histone H2A variant H2AZ is an essential chromatin signaling factor. Herein, we report
that H2AZ is monomethylated at lysine 7 (H2AZK7me1) by the lysine methyltransferase …

Trimethylation of histone H3 lysine 4 impairs methylation of histone H3 lysine 9: regulation of lysine methyltransferases by physical interaction with their substrates

O Binda, G LeRoy, DJ Bua, BA Garcia, O Gozani… - Epigenetics, 2010 - Taylor & Francis
… The carboxy-terminally biotinylated histone peptides (330 pmol in 50 µL ddH 2 O) were …
0.05% Tween-20) and twice with ddH 2 O. The KMT reactions were then carried out by adding to …

A chemical method for labeling lysine methyltransferase substrates

O Binda, M Boyce, JS Rush, KK Palaniappan… - …, 2011 - Wiley Online Library
Several protein lysine methyltransferases (PKMTs) modify histones to regulate chromatin‐dependent
cellular processes, such as transcription, DNA replication and DNA damage repair. …

[HTML][HTML] ING proteins: tumour suppressors or oncoproteins

K Jacquet, O Binda - Cancers, 2021 - mdpi.com
Simple Summary The INhibitor of Growth (ING) family of proteins was founded when in 1996
ING1 was identified as a tumour suppressor, a protein that prevents cancer development. …