The anticancer activity of antisense microRNA (fRNA) in combination with the lectin from Bacillus subtilis B-7025

…, G Didenko, B Farber, S Farber, O Cruts - Journal of Pharmacy …, 2018 - academic.oup.com
Objectives Many adenocarcinomas have the ability to capture from an extracellular matrix
the oligonucleotides and nanoparticles by pinocytosis, when the non-cancerous cells are not …

A Pan‐European Study of the C9orf72 Repeat Associated with FTLD: Geographic Prevalence, Genomic Instability, and Intermediate Repeats

…, R Vandenberghe, PP De Deyn, M Cruts… - Human …, 2013 - Wiley Online Library
We assessed the geographical distribution of C9orf72 G 4 C 2 expansions in a pan‐ E
uropean frontotemporal lobar degeneration ( FTLD ) cohort (n = 1,205), ascertained by the E …

The anticancer activity and immune modulating properties of combinatorial ensemble complementary (antisense) microRNA (fRNA) in combination with the …

A Martynov, G Didenko, B Farber, S Farber, O Cruts - bioRxiv, 2017 - biorxiv.org
Background Many adenocarcinomas have the ability to capture from an extracellular matrix
the oligonucleotides and nanoparticles by pinocytosis, when the non-cancerous cells are not …

Mapping of a gene predisposing to early–onset Alzheimer's disease to chromosome 14q24. 3

C Van Broeckhoven, H Backhovens, M Cruts… - Nature …, 1992 - nature.com
… In the analysis of AACT we used Southern blot hybridization of StuI digested DNA with a o.-*P
labelled 1.5 … For each amplification one of the primers was end-labelled with o."PusingT4 …

Bidirectional transcripts of the expanded C9orf72 hexanucleotide repeat are translated into aggregating dipeptide repeat proteins

…, SM Weng, MH Schludi, J van der Zee, M Cruts… - Acta …, 2013 - Springer
… Tissue peroxidase was blocked with 5 % H 2 O 2 in methanol for 16 min followed by a brief
rinse with deionized water. Sections were settled in PBS with 0.05 % Brij35. Blocking was …

Frontotemporal dementia and its subtypes: a genome-wide association study

…, W Deschamps, T Van Langenhove, M Cruts… - The Lancet …, 2014 - thelancet.com
Background Frontotemporal dementia (FTD) is a complex disorder characterised by a broad
range of clinical manifestations, differential pathological signatures, and genetic variability. …

Progranulin null mutations in both sporadic and familial frontotemporal dementia

…, M Didic, F Salachas, C Duyckaerts, M Cruts… - Human …, 2007 - Wiley Online Library
Frontotemporal dementia (FTD) is the second most frequent type of neurodegenerative
dementias. Mutations in the progranulin gene (GRN, PGRN) were recently identified in FTDU‐17, …

[HTML][HTML] The C9orf72 repeat size correlates with onset age of disease, DNA methylation and transcriptional downregulation of the promoter

…, P Cras, JJ Martin, PP De Deyn, M Cruts… - Molecular …, 2016 - nature.com
Pathological expansion of a G 4 C 2 repeat, located in the 5'regulatory region of C9orf72, is
the most common genetic cause of frontotemporal lobar degeneration (FTLD) and …

Prospective Belgian study of neurodegenerative and vascular dementia: APOE genotype effects

…, M Van den Broeck, S Serneels, M Cruts… - Journal of Medical …, 2003 - jmg.bmj.com
… The most recent study validating in the context of the Nurses Health study18 produced an
E/O ratio of 0.94 (0.89–0.99) compared with our screening population results, which were …

Model of electrical conductivity of skeletal muscle based on tissue structure

FLH Gielen, HEP Cruts, BA Albers, KL Boon… - Medical and Biological …, 1986 - Springer
… and B o and 2 o are constant. Due to the condition that the extracellular current ie(y )
must have a finite value, B o = 0. The constants Vo and 2o can be found using the following …