… Schleiermacher G, Delattre O: Detection of micrometastases and circulating tumour cells
using molecular biology technics in solid tumours [in French]. Bull Cancer 88:561-570, 2001 47. …

Ewing sarcoma is the second most frequent bone tumour of childhood and adolescence that
can also arise in soft tissue. Ewing sarcoma is a highly aggressive cancer, with a survival of …

The SWI/SNF complexes, initially identified in yeast 20 years ago, are a family of multi-subunit
complexes that use the energy of adenosine triphosphate (ATP) hydrolysis to remodel …

Clinical responses to anticancer therapies are often restricted to a subset of patients. In some
cases, mutated cancer genes are potent biomarkers for responses to targeted agents. Here…

EWING'S sarcoma and related subtypes of primitive neuroectodermal tumours share a recurrent
and specific t(ll;22) (q24;q12) chromosome translocation 1–8 , the breakpoints of which …

… radixin: a large N-terminal domain followed by a large o-helix domain and a small C terminus.
… From these homologies we predict that the N-terminal domain binds to integrins and the o- …

Malignant rhabdoid tumours (MRTs) are extremely aggressive cancers of early childhood.
They can occur in various locations, mainly the kidney, brain and soft tissues 1 , 2 . …

Medulloblastoma is the most common malignant brain tumor in childhood. Molecular studies
from several groups around the world demonstrated that medulloblastoma is not one …

Medulloblastoma, the most common malignant paediatric brain tumour, is currently treated
with nonspecific cytotoxic therapies including surgery, whole-brain radiation, and aggressive …

Smoothened (SMO) inhibitors recently entered clinical trials for sonic-hedgehog-driven
medulloblastoma (SHH-MB). Clinical response is highly variable. To understand the mechanism(…