Evidence of dysregulation of dendritic cells in primary HIV infection

…, L Qin, N Hu, E Taylor, O Dibben… - Blood, The Journal …, 2010 - ashpublications.org
Myeloid and plasmacytoid dendritic cells (DCs) are important mediators of both innate and
adaptive immunity against pathogens such as HIV. During the course of HIV infection, blood …

[HTML][HTML] Relative resistance of HIV-1 founder viruses to control by interferon-alpha

AE Fenton-May, O Dibben, T Emmerich, H Ding… - Retrovirology, 2013 - Springer
Background Following mucosal human immunodeficiency virus type 1 (HIV-1) transmission,
type 1 interferons (IFNs) are rapidly induced at sites of initial virus replication in the mucosa …

Multisite comparison of high-sensitivity multiplex cytokine assays

…, L Magpantay, CB Mulder, O Dibben… - Clinical and Vaccine …, 2011 - Am Soc Microbiol
The concentrations of cytokines in human serum and plasma can provide valuable information
about in vivo immune status, but low concentrations often require high-sensitivity assays …

[HTML][HTML] HIV-1 populations in semen arise through multiple mechanisms

JA Anderson, LH Ping, O Dibben, CB Jabara… - PLoS …, 2010 - journals.plos.org
HIV-1 is present in anatomical compartments and bodily fluids. Most transmissions occur
through sexual acts, making virus in semen the proximal source in male donors. We find three …

Exercise-based cardiac rehabilitation for coronary heart disease: a meta-analysis

GO Dibben, J Faulkner, N Oldridge, K Rees… - European heart …, 2023 - academic.oup.com
Aims Coronary heart disease is the most common reason for referral to exercise-based cardiac
rehabilitation (CR) globally. However, the generalizability of previous meta-analyses of …

[HTML][HTML] Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy

C Gay, O Dibben, JA Anderson, A Stacey, AJ Mayo… - PloS one, 2011 - journals.plos.org
Background Acute HIV infection (AHI) is a critical phase of infection when irreparable damage
to the immune system occurs and subjects are very infectious. We studied subjects with …

Cardiac rehabilitation and physical activity: systematic review and meta-analysis

GO Dibben, HM Dalal, RS Taylor, P Doherty, LH Tang… - Heart, 2018 - heart.bmj.com
Objective To undertake a systematic review and meta-analysis to assess the impact of cardiac
rehabilitation (CR) on physical activity (PA) levels of patients with heart disease and the …

Replication of live attenuated influenza vaccine viruses in human nasal epithelial cells is associated with H1N1 vaccine effectiveness

…, R Lockhart, J Crowe, R Maeso, L Ritter, O Dibben… - Vaccine, 2020 - Elsevier
In the 2013–2014 and 2015–2016 influenza seasons, live attenuated influenza vaccine (LAIV)
generated reduced vaccine effectiveness (VE) against circulating H1N1 strains. This …

[HTML][HTML] Defining the root cause of reduced H1N1 live attenuated influenza vaccine effectiveness: low viral fitness leads to inter-strain competition

O Dibben, J Crowe, S Cooper, L Hill, KE Schewe… - NPJ vaccines, 2021 - nature.com
… Further information and requests for resources and reagents should be directed to and
will be fulfilled by the Lead Contact, Oliver Dibben (oliver.dibben@astrazeneca.com). …

[HTML][HTML] A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon

MB Ortigoza, O Dibben, J Maamary… - PLoS …, 2012 - journals.plos.org
Influenza viruses continue to pose a major public health threat worldwide and options for
antiviral therapy are limited by the emergence of drug-resistant virus strains. The antiviral …