Computational strategies to combat COVID-19: useful tools to accelerate SARS-CoV-2 and coronavirus research
…, S Chuguransky, O Drechsel… - Briefings in …, 2021 - academic.oup.com
SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) is a novel virus of the
family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of …
family Coronaviridae. The virus causes the infectious disease COVID-19. The biology of …
OrganellarGenomeDRAW—a suite of tools for generating physical maps of plastid and mitochondrial genomes and visualizing expression data sets
M Lohse, O Drechsel, S Kahlau… - Nucleic acids research, 2013 - academic.oup.com
Mitochondria and plastids (chloroplasts) are cell organelles of endosymbiotic origin that
possess their own genetic information. Most organellar DNAs map as circular double-stranded …
possess their own genetic information. Most organellar DNAs map as circular double-stranded …
OrganellarGenomeDRAW (OGDRAW): a tool for the easy generation of high-quality custom graphical maps of plastid and mitochondrial genomes
M Lohse, O Drechsel, R Bock - Current genetics, 2007 - Springer
… Two minor annotation errors should be changed by editing the GenBank entry in a text editor:
(1) The RNA subunit of RNase P (rnpB; at approximately nine o’clock) is misannotated as …
(1) The RNA subunit of RNase P (rnpB; at approximately nine o’clock) is misannotated as …
[PDF][PDF] HMGB2 loss upon senescence entry disrupts genomic organization and induces CTCF clustering across cell types
…, JP Mallm, CA Brackley, H Gothe, O Drechsel… - Molecular cell, 2018 - cell.com
Processes like cellular senescence are characterized by complex events giving rise to
heterogeneous cell populations. However, the early molecular events driving this cascade remain …
heterogeneous cell populations. However, the early molecular events driving this cascade remain …
Missense mutations in TENM4, a regulator of axon guidance and central myelination, cause essential tremor
…, A Gironell, J Clarimón, O Drechsel… - Human molecular …, 2015 - academic.oup.com
Essential tremor (ET) is a common movement disorder with an estimated prevalence of 5%
of the population aged over 65 years. In spite of intensive efforts, the genetic architecture of …
of the population aged over 65 years. In spite of intensive efforts, the genetic architecture of …
[HTML][HTML] Spatial chromosome folding and active transcription drive DNA fragility and formation of oncogenic MLL translocations
…, R Piccinno, G Petrosino, S Sayols, O Drechsel… - Molecular cell, 2019 - cell.com
How spatial chromosome organization influences genome integrity is still poorly understood.
Here, we show that DNA double-strand breaks (DSBs) mediated by topoisomerase 2 (TOP2…
Here, we show that DNA double-strand breaks (DSBs) mediated by topoisomerase 2 (TOP2…
[HTML][HTML] Effects of caloric restriction on the gut microbiome are linked with immune senescence
…, S Brachs, K Mai, A Thürmer, A Radonić, O Drechsel… - Microbiome, 2022 - Springer
… Directly prior to analysis, cells were resuspended in ddH 2 O, filtered through a 20-μm cell
strainer (Celltrics, Sysmex), counted and adjusted to max. 8 × 10 5 cells/ml. EQ four element …
strainer (Celltrics, Sysmex), counted and adjusted to max. 8 × 10 5 cells/ml. EQ four element …
[HTML][HTML] Changes in free polyamine levels, expression of polyamine biosynthesis genes, and performance of rice cultivars under salt stress: a comparison with …
PT Do, O Drechsel, AG Heyer, DK Hincha… - Frontiers in Plant …, 2014 - frontiersin.org
Soil salinity affects a large proportion of rural area and limits agricultural productivity. To
investigate differential adaptation to soil salinity, we studied salt tolerance of 18 varieties of …
investigate differential adaptation to soil salinity, we studied salt tolerance of 18 varieties of …
Advancing precision vaccinology by molecular and genomic surveillance of severe acute respiratory syndrome coronavirus 2 in Germany, 2021
…, A Brinkmann, K Trappe, O Drechsel… - Clinical infectious …, 2022 - academic.oup.com
Background Comprehensive pathogen genomic surveillance represents a powerful tool to
complement and advance precision vaccinology. The emergence of the Alpha variant in …
complement and advance precision vaccinology. The emergence of the Alpha variant in …
[HTML][HTML] Heatwave-associated Vibrio infections in Germany, 2018 and 2019
…, MS Martins, S Dupke, D Jacob, O Drechsel… - …, 2021 - eurosurveillance.org
… In addition, conventional PCRs for the determination of serotype serogroup-specific gene
rfb were performed to confirm the identification of non-O:1/non-O:139 V. cholerae strains. …
rfb were performed to confirm the identification of non-O:1/non-O:139 V. cholerae strains. …