User profiles for O. G. Pybus

Oliver Pybus

University of Oxford / Royal Veterinary College
Verified email at zoo.ox.ac.uk
Cited by 75969

Unifying the epidemiological and evolutionary dynamics of pathogens

BT Grenfell, OG Pybus, JR Gog, JLN Wood, JM Daly… - science, 2004 - science.org
A key priority for infectious disease research is to clarify how pathogen genetic variation,
modulated by host immunity, transmission bottlenecks, and epidemic dynamics, determines the …

[HTML][HTML] Evolutionary analysis of the dynamics of viral infectious disease

OG Pybus, A Rambaut - Nature Reviews Genetics, 2009 - nature.com
Many organisms that cause infectious diseases, particularly RNA viruses, mutate so rapidly
that their evolutionary and ecological behaviours are inextricably linked. Consequently, …

SARS-CoV-2 evolution in the Omicron era

…, K Sato, Á O'Toole, A Rambaut, OG Pybus… - Nature …, 2023 - nature.com
Since SARS-CoV-2 BA.5 (Omicron) emerged and spread in 2022, Omicron lineages have
markedly diversified. Here we review the evolutionary trajectories and processes that …

[HTML][HTML] A dynamic nomenclature proposal for SARS-CoV-2 lineages to assist genomic epidemiology

…, JT McCrone, C Ruis, L du Plessis, OG Pybus - Nature …, 2020 - nature.com
The ongoing pandemic spread of a new human coronavirus, SARS-CoV-2, which is associated
with severe pneumonia/disease (COVID-19), has resulted in the generation of tens of …

[HTML][HTML] Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa

…, F Treurnicht, M Venter, C Williamson, OG Pybus… - Nature, 2022 - nature.com
The SARS-CoV-2 epidemic in southern Africa has been characterized by three distinct waves.
The first was associated with a mix of SARS-CoV-2 lineages, while the second and third …

Bayesian coalescent inference of past population dynamics from molecular sequences

…, A Rambaut, B Shapiro, OG Pybus - Molecular biology and …, 2005 - academic.oup.com
We introduce the Bayesian skyline plot, a new method for estimating past population
dynamics through time from a sample of molecular sequences without dependence on a …

Genomics and epidemiology of the P. 1 SARS-CoV-2 lineage in Manaus, Brazil

…, A Rambaut, NA Fraiji, MPSS Carvalho, OG Pybus… - Science, 2021 - science.org
Cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in
Manaus, Brazil, resurged in late 2020 despite previously high levels of infection. Genome …

The effect of human mobility and control measures on the COVID-19 epidemic in China

…, M Layan, A Vespignani, H Tian, C Dye, OG Pybus… - Science, 2020 - science.org
The ongoing coronavirus disease 2019 (COVID-19) outbreak expanded rapidly throughout
China. Major behavioral, clinical, and state interventions were undertaken to mitigate the …

[HTML][HTML] Emergence of SARS-CoV-2 omicron lineages BA. 4 and BA. 5 in South Africa

…, SL Kosakovsky Pond, C Williamson, OG Pybus… - Nature medicine, 2022 - nature.com
Three lineages (BA.1, BA.2 and BA.3) of the severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa’s fourth …

[HTML][HTML] Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic

…, J Bahl, SJ Lycett, M Worobey, OG Pybus… - Nature, 2009 - nature.com
In March and early April 2009, a new swine-origin influenza A (H1N1) virus (S-OIV) emerged
in Mexico and the United States 1 . During the first few weeks of surveillance, the virus …