A metastable prerequisite for the growth of lumazine synthase crystals

O Gliko, N Neumaier, W Pan, I Haase… - Journal of the …, 2005 - ACS Publications
Dense liquid phases, metastable with respect to a solid phase, form in solutions of proteins
and small-molecule materials. They have been shown to serve as a prerequisite for the …

Metastable liquid clusters in super-and undersaturated protein solutions

O Gliko, W Pan, P Katsonis, N Neumaier… - The Journal of …, 2007 - ACS Publications
Dense liquid phases, metastable with respect to a solid phase, but stable with respect to the
solution, have been known to form in solutions of proteins and small-molecule substances. …

Single-cell transcriptomic evidence for dense intracortical neuropeptide networks

…, F Collman, S Seshamani, R Gala, O Gliko… - elife, 2019 - elifesciences.org
… : Gi/o (blue) in the EfiE quadrant, Gs (green) in the EfiI quadrant, and Gi/o (red) in the IfiI
and IfiE quadrants. (5) As is particularly notable in the component matrix plots, Gi/o (red) …

Diffusion-limited kinetics of the solution–solid phase transition of molecular substances

DN Petsev, K Chen, O Gliko… - Proceedings of the …, 2003 - National Acad Sciences
… We thank JJ DeYoreo for generously sharing unpublished results; O. Galkin and AA Chernov
for numerous critical suggestions; BR Thomas for supplying purified proteins used in the …

[HTML][HTML] Carbon nanotubes: solution for the therapeutic delivery of siRNA?

…, A Naumov, G Bartholomeusz, RB Weisman, O Gliko - Materials, 2012 - mdpi.com
… have been developed into sensing devices for human disease including for the detection of
lung cancer and kidney disease in human breath, glucose levels in diabetics and H 2 O 2 in …

Molecular mechanisms of microheterogeneity‐induced defect formation in ferritin crystallization

ST Yau, BR Thomas, O Galkin, O Gliko… - Proteins: Structure …, 2001 - Wiley Online Library
We apply in situ atomic force microscopy to the crystallization of ferritins from solutions
containing ≈5% (w/w) of their inherent molecular dimers. Molecular resolution imaging shows …

Enhancement and suppression of protein crystal nucleation due to electrically driven convection

A Penkova, O Gliko, IL Dimitrov, FV Hodjaoglu… - Journal of Crystal …, 2005 - Elsevier
We investigated the effects of the constant electric fields from 2.0 to 6.0kVcm −1 on the
nucleation of ferritin, apoferritin and lysozyme crystals. For this, supersaturated solutions of the …

[HTML][HTML] Connecting single-cell transcriptomes to projectomes in mouse visual cortex

…, M Mallory, A Budzillo, R Dalley, B Lee, O Gliko… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The mammalian brain is composed of diverse neuron types that play different functional
roles. Recent single-cell RNA sequencing approaches have led to a whole brain taxonomy of …

Dense liquid droplets as a step source for the crystallization of lumazine synthase

O Gliko, N Neumaier, M Fischer, I Haase… - Journal of Crystal …, 2005 - Elsevier
We use atomic force microscopy to explore the mechanisms of crystal growth of the protein
lumazine synthase. We find that at moderate supersaturations, the only mechanism of layer …

Stable equidistant step trains during crystallization of insulin

O Gliko, I Reviakine, PG Vekilov - Physical review letters, 2003 - APS
Bunching of growth steps plagues layerwise crystallization of materials in laboratory,
industrial, and geological environments, and theory predicts that equidistant step trains are …