The exon junction complex (EJC) is a central effector of the fate of mRNAs, linking nuclear
processing to mRNA transport, translation and surveillance. However, little is known about its …

IL-13–induced goblet cell metaplasia contributes to airway remodeling and pathological mucus
hypersecretion in asthma. miRNAs are potent modulators of cellular responses, but their …

Quiescent leukemic cells survive chemotherapy, with translation changes. Our data reveal
that FXR1, a protein amplified in several aggressive cancers, is elevated in quiescent and …

Compared to coding sequences, untranslated regions of the transcriptome are not well
conserved, and functional annotation of these sequences is challenging. Global relationships …

The early development of many animals relies on the posttranscriptional regulations of
maternally stored mRNAs. In particular, the translation of maternal mRNAs is tightly controlled …

AU-rich elements (AREs) are 3′ UTR cis-regulatory elements that regulate the stability of
mRNAs. Consensus ARE motifs have been determined, but little is known about how …

FXR1 belongs to a family of RNA-binding proteins that play critical roles in post-transcriptional
regulation of gene expression in immunity, development and cancer. FXR1 is associated …

The specific interactions between RNA-binding proteins and their target RNAs are an
essential level to control gene expression. By combining ultra-violet cross-linking and …

CUGBP1 is an RNA-binding protein controlling alternative splicing, mRNA translation and
stability. In this work we used a motif scoring approach to identify putative CUGBP1 binding …

… Eleni Chantzoura 1 , Efrat Altman Sharoni 1 , Reed Masakayan 1 , Martyna Popis 1 , Darrian
Moskowitz 1 , Paul Ibbett 1 , Sapana Pokharel 1 , Moira Pinzan Rossi 1 , Deborah Wright 1 …