This review discusses the cerebral plasticity, and the role of the cortico-striatal system in
particular, observed as one is learning or planning to execute a newly learned motor behavior …

Cognitive abnormalities are a feature of Parkinson's disease (PD). Unlike motor symptoms
that are clearly improved by dopaminergic therapy, the effect of dopamine replacement on …

Background Human genetics research lacks diversity; over 80% of genome‐wide association
studies have been conducted on individuals of European ancestry. In addition to limiting …

The Wisconsin Card Sorting Task (WCST) has been used to assess dysfunction of the
prefrontal cortex and basal ganglia. Previous brain imaging studies have focused on identifying …

Objective Recent studies of functional brain imaging have shown the involvement of the basal
ganglia in executive processes such as planning and set‐shifting. However, the specific …

Patients with Parkinson's disease (PD) exhibit impairments in several cognitive functions
similar to those observed in patients with prefrontal cortex (PFC) lesions. The physiological …

Objective To examine the integrity of the default mode network in patients with Parkinson
disease (PD). Previous functional neuroimaging experiments have studied executive deficits in …

Patients with idiopathic Parkinson's disease exhibit impairments in executive processes,
including planning and set-shifting, even at the early stages of the disease. We have recently …

We investigated the effect of transient dopamine depletion on functional connectivity during
performance of the Wisconsin Card Sorting Task. Functional magnetic resonance imaging …

Background Cognitive impairment is a frequent feature of COPD. However, the proportion of
patients with COPD with mild cognitive impairment (MCI) is still unknown, and no screening …