Matrix metalloproteinases (MMPs) are members of the metzincin group of proteases which
share the conserved zinc-binding motif in their catalytic active site. It was originally thought …

Fibroblast activation protein (FAP) is best known for its heightened expression in tumour stroma.
This atypical serine protease has both dipeptidyl peptidase and endopeptidase activities…

… V(O). This convention is plausible if we observe that O = x‘O for all integers a. The valuation
V determines in F two subsets O and P Where a Q 0 if and only if V(a) ; 0 and b EP if and …

Background In recent years, several mass spectrometry-based omics technologies emerged
to investigate qualitative and quantitative changes within thousands of biologically active …

As tissue macrophages of the central nervous system (CNS), microglia constitute the pivotal
immune cells of this organ. Microglial features are strongly dependent on environmental …

High-resolution mass spectrometry (MS) has become an important tool in the life sciences,
contributing to the diagnosis and understanding of human diseases, elucidating biomolecular …

… kDa (1 g) was dissolved in 10 ml of ddH 2 O, followed by the addition of 0.9 g of HIO 4 (HPG-…
against ddH 2 O using 1,000 MWCO membrane for 48 h with 8 changes of ddH 2 O. The …

Purpose: The aim of this work is to examine the relationship between aspects of objective
and perceived housing and aspects of healthy aging, defined as independence in daily …

Cancer cell invasion takes place at the cancer–host interface and is a prerequisite for distant
metastasis. The relationships between current biological and clinical concepts such as cell …

We introduce human proteome–derived, database-searchable peptide libraries for characterizing
sequence-specific protein interactions. To identify endoprotease cleavage sites, we …