User profiles for OB Pedersen

Oluf Pedersen

- Verified email at sund.ku.dk - Cited by 232166

Ole B. Pedersen

- Verified email at regionsjaelland.dk - Cited by 6148

[HTML][HTML] A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis

…, V Tragante, P Surendran, OB Pedersen… - Communications …, 2021 - nature.com
Iron is essential for many biological functions and iron deficiency and overload have major
health implications. We performed a meta-analysis of three genome-wide association studies …

[HTML][HTML] The sequences of 150,119 genomes in the UK Biobank

…, AJ Geirsson, I Olafsson, P Jonsson, OB Pedersen… - Nature, 2022 - nature.com
Detailed knowledge of how diversity in the sequence of the human genome affects phenotypic
diversity depends on a comprehensive and reliable characterization of both sequences …

The application of the Eshelby method of internal stress determination to short fibre metal matrix composites

PJ Withers, WM Stobbs, OB Pedersen - Acta Metallurgica, 1989 - Elsevier
Eshelby's equivalent inclusion approach is used to provide a rigorous theoretical basis for the
prediction of the mechanical properties of short fibre composites. The equivalent inclusion …

[HTML][HTML] Multiomics study of nonalcoholic fatty liver disease

…, GR Oskarsson, SR Ostrowski, OB Pedersen… - Nature …, 2022 - nature.com
Nonalcoholic fatty liver (NAFL) and its sequelae are growing health problems. We performed
a genome-wide association study of NAFL, cirrhosis and hepatocellular carcinoma, and …

Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial

…, CT Ekstrøm, C Ritz, HB Nielsen, OB Pedersen… - Gut, 2019 - gut.bmj.com
Objective To investigate whether a whole grain diet alters the gut microbiome and insulin
sensitivity, as well as biomarkers of metabolic health and gut functionality. Design 60 Danish …

[HTML][HTML] Genome-wide analysis of 102,084 migraine cases identifies 123 risk loci and subtype-specific risk alleles

…, L Lighart, SH Magnusson, R Malik, OB Pedersen… - Nature …, 2022 - nature.com
Migraine affects over a billion individuals worldwide but its genetic underpinning remains
largely unknown. Here, we performed a genome-wide association study of 102,084 migraine …

[HTML][HTML] Acute and persistent symptoms in non-hospitalized PCR-confirmed COVID-19 patients

S Bliddal, K Banasik, OB Pedersen, J Nissen… - Scientific reports, 2021 - nature.com
Reports of persistent symptoms after hospitalization with COVID-19 have raised concern of a
“long COVID” syndrome. This study aimed at determining the prevalence of and risk factors …

Aberrant gut microbiota alters host metabolome and impacts renal failure in humans and rodents

…, DH Shao, J Li, Y Zhou, S Li, R Yang, OB Pedersen… - Gut, 2020 - gut.bmj.com
Objective Patients with renal failure suffer from symptoms caused by uraemic toxins, possibly
of gut microbial origin, as deduced from studies in animals. The aim of the study is to …

Genome-wide meta-analysis identifies 93 risk loci and enables risk prediction equivalent to monogenic forms of venous thromboembolism

…, K Banasik, S Brunak, SR Ostrowski, OB Pedersen… - Nature Genetics, 2023 - nature.com
We report a genome-wide association study of venous thromboembolism (VTE) incorporating
81,190 cases and 1,419,671 controls sampled from six cohorts. We identify 93 risk loci, of …

Heritability of psoriasis in a large twin sample

…, A Skytthe, KO Kyvik, OB Pedersen… - British Journal of …, 2013 - academic.oup.com
Background Previous twin studies have shown greater concordance rates for psoriasis in MZ
than in DZ twins, and heritability estimates between 66% and 90%. This supports a genetic …