User profiles for Oana A. Zeleznik

Oana A Zeleznik

Harvard Medical School and Brigham and Women's Hospital
Verified email at channing.harvard.edu
Cited by 1503

Dimension reduction techniques for the integrative analysis of multi-omics data

C Meng, OA Zeleznik, GG Thallinger… - Briefings in …, 2016 - academic.oup.com
Zeleznik Oana Zeleznik has recently defended her thesis ‘Integrative Analysis of Omics Data.
Enhancement of Existing Methods and … He supervised Oana Zeleznik’s graduate studies. …

A prospective analysis of circulating plasma metabolites associated with ovarian cancer risk

OA Zeleznik, AH Eliassen, P Kraft, EM Poole… - Cancer research, 2020 - AACR
Oana A. Zeleznik … Development of methodology: OA Zeleznik

Deciphering lipid structures based on platform-independent decision rules

…, A Ziegl, M Trötzmüller, GN Rechberger, OA Zeleznik… - Nature …, 2017 - nature.com
We achieve automated and reliable annotation of lipid species and their molecular structures
in high-throughput data from chromatography-coupled tandem mass spectrometry using …

[HTML][HTML] Plasma metabolite profile for primary open-angle glaucoma in three US cohorts and the UK Biobank

OA Zeleznik, JH Kang, J Lasky-Su, AH Eliassen… - Nature …, 2023 - nature.com
Glaucoma is a progressive optic neuropathy and a leading cause of irreversible blindness
worldwide. Primary open-angle glaucoma is the most common form, and yet the etiology of …

Stability and reproducibility of proteomic profiles in epidemiological studies: comparing the Olink and SOMAscan platforms

…, J Li, ST Dillon, X Gu, Y Cao, OA Zeleznik… - …, 2022 - Wiley Online Library
Limited data exist on the performance of high‐throughput proteomics profiling in epidemiological
settings, including the impact of specimen collection and within‐person variability over …

[HTML][HTML] Integration of metabolomic and other omics data in population-based study designs: an epidemiological perspective

…, RS Kelly, E Benedetti, JK Siddiqui, OA Zeleznik… - Metabolites, 2019 - mdpi.com
It is not controversial that study design considerations and challenges must be addressed
when investigating the linkage between single omic measurements and human phenotypes. It …

Obesity-related metabolomic profiles and discrimination of metabolically unhealthy obesity

…, M Chamari, OA Zeleznik… - Journal of proteome …, 2018 - ACS Publications
A particular subgroup of obese adults, considered as metabolically healthy obese (MHO),
has a reduced risk of metabolic complications. However, the molecular basis contributing to …

[HTML][HTML] Intrapersonal stability of plasma metabolomic profiles over 10 years among women

OA Zeleznik, C Wittenbecher, A Deik, S Jeanfavre… - Metabolites, 2022 - mdpi.com
In epidemiological studies, samples are often collected long before disease onset or
outcome assessment. Understanding the long-term stability of biomarkers measured in these …

Metabolomic signatures of long-term coffee consumption and risk of type 2 diabetes in women

D Hang, OA Zeleznik, X He, M Guasch-Ferre… - Diabetes …, 2020 - Am Diabetes Assoc
OBJECTIVE Coffee may protect against multiple chronic diseases, particularly type 2 diabetes,
but the mechanisms remain unclear. RESEARCH DESIGN AND METHODS Leveraging …

Habitual sleep quality, plasma metabolites and risk of coronary heart disease in post-menopausal women

T Huang, OA Zeleznik, EM Poole… - International journal …, 2019 - academic.oup.com
Background Epidemiologic studies suggest a strong link between poor habitual sleep quality
and increased cardiovascular disease risk. However, the underlying mechanisms are not …