Obsessive–compulsive disorder (OCD) is a highly prevalent and chronic condition that is
associated with substantial global disability. OCD is the key example of the ‘obsessive–…

Compulsivity is associated with alterations in the structure and the function of parallel and
interacting brain circuits involved in emotional processing (involving both the reward and the …

Background Dysfunction of frontal-striatal, particularly orbitofrontal-striatal, circuitry has been
implicated in the pathophysiology of obsessive-compulsive disorder (OCD), characterized …

Objective: Structural brain imaging studies in obsessive-compulsive disorder (OCD) have
produced inconsistent findings. This may be partially due to limited statistical power from …

Compulsivity has been recently characterized as a manifestation of an imbalance between
the brain׳s goal-directed and habit-learning systems. Habits are perhaps the most …

Context Attentional bias to disease-relevant emotional cues is considered to be pathogenetically
relevant in anxiety disorders. Objective To investigate functional neural correlates and …

Obsessive–compulsive disorder (OCD) is a clinically heterogeneous disorder characterized
by multiple, temporally stable symptom dimensions. Preliminary functional neuroimaging …

… van den Heuvel … Dvan den Heuvel OA Common and distinct neural correlates of obsessive-…
Radua J, van den Heuvel OA, Surguladze S, Mataix-Cols D. Meta-analytical Comparison of …

Context Major depressive disorder (MDD), panic disorder, and social anxiety disorder are
among the most prevalent and frequently co-occurring psychiatric disorders in adults and may …

BACKGROUND: Brain mechanisms of chronic insomnia, a highly prevalent condition, have
barely been investigated. We demonstrate here a decrease in orbitofrontal gray matter (GM) …