PTP-3 phosphatase promotes intramolecular folding of SYD-2 to inactivate kinesin-3 UNC-104 in neurons

…, SN Barmaver, HY Huang, O Bayansan… - Molecular Biology of …, 2020 - Am Soc Cell Biol
UNC-104 is the Caenorhabditis elegans homolog of kinesin-3 KIF1A known for its fast shuffling
of synaptic vesicle protein transport vesicles in axons. SYD-2 is the homolog of liprin-α in …

Characterization of TAG‐63 and its role on axonal transport in C. elegans

…, M Muthaiyan Shanmugam, D Wang, O Bayansan… - Traffic, 2020 - Wiley Online Library
Abstract Model organisms are increasingly used to study and understand how neurofilament
(NF)‐based neurological diseases develop. However, whether a NF homolog exists in C. …

Loss of intermediate filament IFB‐1 reduces mobility, density, and physiological function of mitochondria in Caenorhabditis elegans sensory neurons

…, M Muthaiyan Shanmugam, Y Chang, O Bayansan… - Traffic, 2022 - Wiley Online Library
Mitochondria and intermediate filament (IF) accumulations often occur during imbalanced
axonal transport leading to various types of neurological diseases. It is still poorly understood …

Understanding the effect of tubulin post‐translational modifications on axonal transport in C. elegans

O Bayansan - The FASEB Journal, 2021 - Wiley Online Library
A remarkable number of post‐translational modifications (PTMs) on tubulin and microtubules
(MTs) have been identified that affect MT dynamic, stability, organization and its interaction …

UNC-10/SYD-2 complex is sufficient to link kinesin-3 to RAB-3 containing synaptic vesicles in the absence of the motor's PH domain

P Bhan, O Bayansan, CY Chang, SN Barmaver… - bioRxiv, 2019 - biorxiv.org
Kinesin-3 KIF1A (UNC-104 in C. elegans) is the major fast axonal transporter of STVs (synaptic
vesicle protein transport vesicles) containing synaptic precursors such as RAB3A (RAB-3…

Deciphering function and the molecular pathways of a novel identified regulator SFXN‐1.2 in mitochondrial dynamics and its effects on worm behavior and …

S Barmaver, O Bayansan - The FASEB Journal, 2021 - Wiley Online Library
Mislocalizations of mitochondria and alterations in mitochondrial dynamics are the hallmarks
in various neurological diseases. Thus, it is critical to understand how the dynamics of …

[PDF][PDF] Dual linker UNC-10/SYD-2 is sufficient to bind kinesin-3 UNC-104 to RAB-3 containing synaptic vesicles in the absence of the motor's PH domain

P Bhan, O Bayansan, CY Chang, OI Wagner - researchgate.net
KIF1A (UNC-104 in C. elegans) is the major fast axonal transporter of synaptic vesicles and
heritable mutations in neuronal motor proteins (and their adaptors) lead to numerous …

[PDF][PDF] UNC-10/SYD-2 complex is sufficient to link kinesin-3 UNC-104 to RAB-3 containing synaptic vesicles in the absence of the motor's PH domain

P Bhan, O Bayansan, CY Chang, OI Wagner - academia.edu
ABSTRACT KIF1A (UNC-104 in C. elegans) is the major fast axonal transporter of STVs
(synaptic vesicle protein transport vesicles) containing synaptic precursors such as RAB-3 or …

[PDF][PDF] Characterization of TAG-63 and its role on axonal transport

P Bhan, MM Shanmugam, D Wang, O Bayansan… - 2019 - researchgate.net
Abstract Model organisms are increasingly used to study and understand how neurofilament
(NF)-based neurological diseases develop. However, whether a NF homolog exists in C. …

RSY-1 Is a Local Inhibitor of Presynaptic Assembly in C. elegans

MR Patel, K Shen - Science, 2009 - science.org
As fundamental units of neuronal communication, chemical synapses are composed of
presynaptic and postsynaptic specializations that form at specific locations with defined shape …