User profiles for Olaf Tyc

Olaf Tyc, Ph.D.

Department of Internal Medicine I, Goethe University Hospital
Verified email at med.uni-frankfurt.de
Cited by 1293

The ecological role of volatile and soluble secondary metabolites produced by soil bacteria

O Tyc, C Song, JS Dickschat, M Vos, P Garbeva - Trends in microbiology, 2017 - cell.com
The rich diversity of secondary metabolites produced by soil bacteria has been appreciated
for over a century, and advances in chemical analysis and genome sequencing continue to …

Involvement of Burkholderiaceae and sulfurous volatiles in disease-suppressive soils

VJ Carrión, V Cordovez, O Tyc, DW Etalo… - The ISME …, 2018 - academic.oup.com
Disease-suppressive soils are ecosystems in which plants suffer less from root infections
due to the activities of specific microbial consortia. The characteristics of soils suppressive to …

[HTML][HTML] Impact of interspecific interactions on antimicrobial activity among soil bacteria

O Tyc, M van den Berg, S Gerards… - Frontiers in …, 2014 - frontiersin.org
Certain bacterial species produce antimicrobial compounds only in the presence of a competing
species. However, little is known on the frequency of interaction-mediated induction of …

[HTML][HTML] Volatiles in inter-specific bacterial interactions

O Tyc, H Zweers, W De Boer, P Garbeva - Frontiers in microbiology, 2015 - frontiersin.org
The importance of volatile organic compounds for functioning of microbes is receiving increased
research attention. However, to date very little is known on how inter-specific bacterial …

Exploring bacterial interspecific interactions for discovery of novel antimicrobial compounds

O Tyc, VCL de Jager, M van den Berg… - Microbial …, 2017 - Wiley Online Library
Recent studies indicated that the production of secondary metabolites by soil bacteria can
be triggered by interspecific interactions. However, little is known to date about interspecific …

[HTML][HTML] Colon cancer microbiome landscaping: differences in right-and left-sided colon cancer and a tumor microbiome-ileal microbiome association

…, AR Siebenhüner, R Schierwagen, O Tyc… - International Journal of …, 2023 - mdpi.com
In the current era of precision oncology, it is widely acknowledged that CRC is a heterogeneous
disease entity. Tumor location (right- or left-sided colon cancer or rectal cancer) is a …

[HTML][HTML] Controlling the microbiome: microhabitat adjustments for successful biocontrol strategies in soil and human gut

…, V Kurm, M Rajewska, R Schmidt, O Tyc… - Frontiers in …, 2016 - frontiersin.org
The human gut and the rhizosphere are environments colonized by highly diverse communities
of microbes, which perform complex interactions with their host and carry out important …

The ecological role of bacterial seed endophytes associated with wild cabbage in the United Kingdom

O Tyc, R Putra, R Gols, JA Harvey… - MicrobiologyOpen, 2020 - Wiley Online Library
Endophytic bacteria are known for their ability in promoting plant growth and defense against
biotic and abiotic stress. However, very little is known about the microbial endophytes …

[HTML][HTML] No Apparent Costs for Facultative Antibiotic Production by the Soil Bacterium Pseudomonas fluorescens Pf0-1

P Garbeva, O Tyc, MNP Remus-Emsermann… - PLoS …, 2011 - journals.plos.org
Background Many soil-inhabiting bacteria are known to produce secondary metabolites that
can suppress microorganisms competing for the same resources. The production of …

[HTML][HTML] The specific NLRP3 antagonist IFM-514 decreases fibrosis and inflammation in experimental murine non-alcoholic steatohepatitis

…, FE Uschner, S Klein, C Ortiz, O Tyc… - Frontiers in Molecular …, 2021 - frontiersin.org
Background and Aims: Activation of the inflammasome NLRP3 (NOD-, LRR- and pyrin
domain containing 3) contributes to the development of non-alcoholic fatty liver disease (NAFLD) …