User profiles for Olena Berkovska

Olena Berkovska

Karolinska Institutet
Verified email at ki.se
Cited by 66

Proteogenomics of non-small cell lung cancer reveals molecular subtypes associated with specific therapeutic targets and immune-evasion mechanisms

…, T Arslan, I Siavelis, Y Pan, F Socciarelli, O Berkovska… - Nature cancer, 2021 - nature.com
Despite major advancements in lung cancer treatment, long-term survival is still rare and a
deeper understanding of molecular phenotypes would allow the identification of specific …

[HTML][HTML] A microparticulate based formulation to protect therapeutic enzymes from proteolytic digestion: phenylalanine ammonia lyase as case study

I Pereira de Sousa, C Gourmel, O Berkovska… - Scientific reports, 2020 - nature.com
Phenylketonuria is a genetic disorder affecting the metabolism of phenylalanine (phe) due to
a deficiency in the enzyme phenylalanine hydroxylase. This disorder is characterized by an …

[HTML][HTML] Bioinformatics analysis of NSCLC multi-omics data

…, T Arslan, I Siavelis, Y Pan, F Socciarelli, O Berkovska… - 2021 - researchsquare.com
The associated publication reports proteogenomic analysis of non-small cell lung cancer (NSCLC),
where we identified molecular subtypes with distinct immune evasion mechanisms …

[HTML][HTML] Mass spectrometry-based proteomic analysis of NSCLC tumor and biopsy samples

…, T Arslan, I Siavelis, Y Pan, F Socciarelli, O Berkovska… - 2021 - researchsquare.com
The associated publication reports proteogenomic analysis of non-small cell lung cancer,
where we identified molecular subtypes with distinct immune evasion mechanisms and …

[HTML][HTML] Immune landscape evaluation of NSCLC clinical samples

…, T Arslan, I Siavelis, Y Pan, F Socciarelli, O Berkovska… - 2021 - researchsquare.com
The associated publication reports proteogenomic analysis of non-small cell lung cancer,
where we identified molecular subtypes with distinct immune evasion mechanisms and …

[HTML][HTML] STK11 pathway in vitro validation

…, T Arslan, I Siavelis, Y Pan, F Socciarelli, O Berkovska… - 2021 - researchsquare.com
The associated publication reports proteogenomic analysis of non-small cell lung cancer (NSCLC),
where we identified molecular subtypes with distinct immune evasion mechanisms …

[PDF][PDF] Engineering Protease-Responsive Microbubbles for Ultrasound-Based Diagnostics

D Dubey - 2022 - research-collection.ethz.ch
Tools for detecting the activity of proteolytic enzymes could potentially transform point-of-care
diagnostic medicine. Proteases, also known as proteinases or peptidases, are enzymes …

[PDF][PDF] Evaluating targeted combination therapies in EGFR wild-type non-small-cell lung cancer using mass spectrometry-based proteomics

J Thorsson - lup.lub.lu.se
… Next up, I would like to thank Olena Berkovska for providing me with lab protocols, guiding
me in the cell lab and for being available to answer questions when needed. Then, I would …

[HTML][HTML] Lipids and polymers in pharmaceutical technology: Lifelong companions

J Siepmann, A Faham, SD Clas, BJ Boyd… - International journal of …, 2019 - Elsevier
In pharmaceutical technology, lipids and polymers are considered pillar excipients for the
fabrication of most dosage forms, irrespective of the administration route. They play various …

[BOOK][B] At the Intersection of Proteomics and Pathology: Application of Mass Spectrometry-Based Protein Quantification to Histopathology and Antibody Validation

F Socciarelli - 2021 - search.proquest.com
The paradigm of Precision Medicine relies on the molecular stratification of patients to select
“the right patient for the right drug”. The genomic approach has tried to answer this question…