Endogenous cardiotonic steroids (CTS), also called digitalis-like factors, have been postulated
to play important roles in health and disease for nearly half a century. Recent discoveries, …

Patients with chronic renal failure develop a “uremic” cardiomyopathy characterized by
diastolic dysfunction, cardiac hypertrophy, and systemic oxidant stress. Patients with chronic …

The interest in functional supramolecular systems for the design of innovative materials and
technologies, able to fundamentally change the world, is growing at a high pace. The huge …

The review describes photoswitchable molecular receptors based on spiropyran, spirooxazine,
and chromene molecules. The presence of coordination centers in their structures …

Objective To determine plasma levels of the endogenous bufodienolide Na+/K+ ATPase
inhibitor, marinobufagenin-like factor (MBG), in normotensive pregnancy and in preeclampsia, …

The review describes photoswitchable molecular receptors based on crown-ether systems.
The important feature of the systems is reversible change in the capacity of a photochromic …

We have observed recently that experimental renal failure in the rat is accompanied by
increases in circulating concentrations of the cardiotonic steroid, marinobufagenin (MBG), and …

Background— Digitalis-like sodium pump ligands (SPLs) effect natriuresis via inhibition of
renal tubular Na + ,K + -ATPase but may induce vasoconstriction. The present study …

Recent evidence suggests the existence of several endogenous Na + ,K + -ATPase inhibitors
in mammals. Previously, we have shown that the amphibian Na + ,K + -ATPase inhibitor …

Cancer immunotherapies that remove checkpoint restraints on adaptive immunity are gaining
clinical momentum but have not achieved widespread success in breast cancers, a tumor …