User profiles for Olga Sizova
 | Olga SizovaPostdoctoral fellow, UT MD Anderson Cancer Center Verified email at mdanderson.org Cited by 238 |
Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens
The adaptation of CRISPR/SpCas9 technology to mammalian cell lines is transforming the
study of human functional genomics. Pooled libraries of CRISPR guide RNAs (gRNAs) …
study of human functional genomics. Pooled libraries of CRISPR guide RNAs (gRNAs) …
Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism
The de novo synthesis of fatty acids has emerged as a therapeutic target for various diseases,
including cancer. Because cancer cells are intrinsically buffered to combat metabolic …
including cancer. Because cancer cells are intrinsically buffered to combat metabolic …
Symmetry decomposition of quantum chemical bond orders
OV Sizova, LV Skripnikov, AY Sokolov - Journal of Molecular Structure …, 2008 - Elsevier
Two schemes based on atomic orbital symmetry for the decomposition of Mayer, B AB , and
Wiberg, W AB , bond order indices into the σ-, π-, and δ-components (AOSB-A) or into the “in-…
Wiberg, W AB , bond order indices into the σ-, π-, and δ-components (AOSB-A) or into the “in-…
[HTML][HTML] Thymic function associated with cancer development, relapse, and antitumor immunity–a mini-review
The thymus is the central lymphoid organ for T cell development, a cradle of T cells, and for
central tolerance establishment, an educator of T cells, maintaining homeostatic cellular …
central tolerance establishment, an educator of T cells, maintaining homeostatic cellular …
[HTML][HTML] ER stress in retinal degeneration in S334ter Rho rats
The S334ter rhodopsin (Rho) rat (line 4) bears the rhodopsin gene with an early termination
codon at residue 334 that is a model for several such mutations found in human patients …
codon at residue 334 that is a model for several such mutations found in human patients …
[HTML][HTML] Multi-drug/gene NASH therapy delivery and selective hyperspectral NIR imaging using chirality-sorted single-walled carbon nanotubes
Single-walled carbon nanotubes (SWCNTs) can serve as drug delivery/biological imaging
agents, as they exhibit intrinsic fluorescence in the near-infrared, allowing for deeper tissue …
agents, as they exhibit intrinsic fluorescence in the near-infrared, allowing for deeper tissue …
[HTML][HTML] Modulation of cellular signaling pathways in P23H rhodopsin photoreceptors
We previously reported activation of the unfolded protein response (UPR) in P23H rhodopsin
(RHO) retinas with autosomal dominant retinitis pigmentosa (ADRP). Knowing that the …
(RHO) retinas with autosomal dominant retinitis pigmentosa (ADRP). Knowing that the …
Synthetic Glycovaccine Protects against the Bite of Leishmania-Infected Sand Flies
Leishmaniasis is a vectorborne disease transmitted to human and other mammalian hosts
by sand fly bite. In the present study, we show that immunization with Leishmania mexicana …
by sand fly bite. In the present study, we show that immunization with Leishmania mexicana …
[HTML][HTML] Multi-faceted role of LRP1 in the immune system
O Sizova, LS John, Q Ma, JJ Molldrem - Frontiers in immunology, 2023 - frontiersin.org
Graft versus host disease (GVHD) represents the major complication after allogeneic
hematopoietic stem cell transplantation (Allo-SCT). GVHD-prone patients rely on GVHD …
hematopoietic stem cell transplantation (Allo-SCT). GVHD-prone patients rely on GVHD …
Luminescent heterometallic gold–copper alkynyl complexes stabilized by tridentate phosphine
…, IO Koshevoy, AS Melnikov, OV Sizova… - Dalton …, 2012 - pubs.rsc.org
The reactions between trinuclear gold complex tppmAu3Cl3 (tppm = tris(diphenylphosphino)methane),
arylacetylenes HC2C6H4X and Cu+ under basic conditions result in formation of …
arylacetylenes HC2C6H4X and Cu+ under basic conditions result in formation of …