The reactions of picolinyl and 4-chloropicolinyl chlorides with methyl esters of S-methyl-l-cysteine,
l- and d-methionine, and l-histidine afforded a series of functionalized carboxamides, …

In the search for potential new metal-based antitumor agents, two series of nonclassical
palladium(II) pincer complexes based on functionalized amides with S-modified cysteine and …

Pincer complexes featuring readily tunable tridentate ligand frameworks comprise one of
the most actively studied classes of organometallic and metal–organic compounds and find …

The efficacy of anthracycline based anticancer drugs is limited by pleiotropic drug resistance
of tumor cells. Aiming at the design of anthracyclinone congeners capable of circumventing …

Background: The evidence that pan-Bcl-2 or Bcl-xL-specific inhibitors prematurely kill virus-infected
or RNA/DNA-transfected cells provides rationale for investigating these apoptotic …

A series of DNA minor groove binding fluorescent dimeric bisbenzimidazoles DBA(n) bearing
linkers of various length were synthesized and their biochemical and antiviral activities …

ortho-Phosphorylated aniline and its thio analog were used as key precursors for the
synthesis of new multidentate ligands based on functionalized monothiooxamides. These …

We describe the synthesis of derivatives of 4,11-diaminonaphtho[2,3-f]indole-5,10-dione
and their cytotoxicity for human tumor cells that express major determinants of altered …

A set of AT-specific fluorescent dimeric bisbenzimidazoles DBPA(n) with linkers of different
lengths bound to DNA in the minor groove were synthesized and their genetic, virological, …

A series of new fluorescent symmetric dimeric bisbenzimidazoles DBP(n) bearing
bisbenzimidazole fragments joined by oligomethylene linkers with a central 1,4-piperazine residue …