Cytolytic proteins and peptide toxins are classical virulence factors of several bacterial
pathogens which disrupt epithelial barrier function, damage cells and activate or modulate host …

Fungi of the order Mucorales colonize all kinds of wet, organic materials and represent a
permanent part of the human environment. They are economically important as fermenting …

Candida auris has emerged globally as a multidrug-resistant yeast that can spread via
nosocomial transmission. An initial phylogenetic study of isolates from Japan, India, Pakistan, …

Scientific communication is facilitated by a data-driven, scientifically sound taxonomy that
considers the end-user’s needs and established successful practice. In 2013, the Fusarium …

Aspergillus fumigatus is an environmental saprobe and opportunistic human fungal pathogen.
Despite an estimated annual occurrence of more than 300,000 cases of invasive disease …

Background The incidence of invasive fungal infection is approximately 6 cases per 100
000 persons per year. It is estimated that only half of such infections are detected during the …

Background Current guidelines recommend empirical antifungal therapy in patients with
sepsis with high risk of invasive Candida infection. However, many different risk factors have …

Background The soluble pattern-recognition receptor known as long pentraxin 3 (PTX3) has
a nonredundant role in antifungal immunity. The contribution of single-nucleotide …

Macrophages and neutrophils kill the airborne fungal pathogen Aspergillus fumigatus. The
dependency of this killing process on reactive oxygen intermediates (ROI) has been strongly …

Introduction Circulating histones have been identified as mediators of damage in animal
models of sepsis and in patients with trauma-associated lung injury. Despite existing …