[HTML][HTML] Preoperative risk factors for conversion from laparoscopic to open cholecystectomy: a validated risk score derived from a prospective UK database of 8820 …

…, K Sarvananthan, SJ Dwerryhouse, SM Higgs, OJ Old… - Hpb, 2016 - Elsevier
Background Laparoscopic cholecystectomy is commonly performed, and several factors
increase the risk of open conversion, prolonging operating time and hospital stay. Preoperative …

[HTML][HTML] Extracorporeal membrane oxygenation in coronavirus disease 2019: A nationwide cohort analysis of 4279 runs from Germany

…, JA Kloka, V Neef, H Mutlak, O Old… - European Journal of …, 2022 - journals.lww.com
BACKGROUND In the context of the coronavirus disease 2019 (COVID-19) pandemic, many
retrospective single-centre or specialised centre reports have shown promising mortality …

[HTML][HTML] Characteristics and mortality of 561,379 hospitalized COVID-19 patients in Germany until December 2021 based on real-life data

JA Kloka, LV Blum, O Old, K Zacharowski… - Scientific reports, 2022 - nature.com
The ongoing SARS-CoV-2 pandemic is characterized by poor outcome and a high mortality
especially in the older patient cohort. Up to this point there is a lack of data characterising …

Identification of prognostic phenotypes of esophageal adenocarcinoma in 2 independent cohorts

…, F Noble, J Owsley, H Barr, N Shepherd, O Old… - Gastroenterology, 2018 - Elsevier
Background & Aims Most patients with esophageal adenocarcinoma (EAC) present with de
novo tumors. Although this could be due to inadequate screening strategies, the precise …

Identification of subtypes of Barrett's esophagus and esophageal adenocarcinoma based on DNA methylation profiles and integration of transcriptome and genome …

…, F Noble, J Owsley, H Barr, N Shepherd, O Old… - Gastroenterology, 2020 - Elsevier
Background & Aims Esophageal adenocarcinomas (EACs) are heterogeneous and often
preceded by Barrett’s esophagus (BE). Many genomic changes have been associated with …

Barrett's Oesophagus Surveillance versus endoscopy at need Study (BOSS): protocol and analysis plan for a multicentre randomized controlled trial

O Old, P Moayyedi, S Love, C Roberts… - Journal of medical …, 2015 - journals.sagepub.com
Objectives The absolute annual risk of patients with Barrett's oesophagus (BO) developing
oesophageal adenocarcinoma (OAC) is ≤0.5%. Screening BO patients for malignant …

Machine learning to predict early recurrence after oesophageal cancer surgery

…, J Owsley, H Barr, N Shepherd, O Old… - Journal of British …, 2020 - academic.oup.com
Background Early cancer recurrence after oesophagectomy is a common problem, with an
incidence of 20–30 per cent despite the widespread use of neoadjuvant treatment. …

Mast cell function: a new vision of an old cell

…, MC Jamur, C Oliver - Journal of Histochemistry …, 2014 - journals.sagepub.com
Since first described by Paul Ehrlich in 1878, mast cells have been mostly viewed as effectors
of allergy. It has been only in the past two decades that mast cells have gained recognition …

The rediscovery of the lymphatic system: old and new insights into the development and biological function of the lymphatic vasculature

G Oliver, M Detmar - Genes & development, 2002 - genesdev.cshlp.org
The lymphatic system is composed of a vascular network of thin-walled capillaries that drain
protein-rich lymph from the extracellular spaces within most organs. A continuous single-cell …

Infrared micro-spectroscopy for cyto-pathological classification of esophageal cells

D Townsend, M Miljković, B Bird, K Lenau, O Old… - Analyst, 2015 - pubs.rsc.org
We report results from a study utilizing infrared spectral cytopathology (SCP) to detect
abnormalities in exfoliated esophageal cells. SCP has been developed over the past decade as …