Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …

Atherosclerosis, a dominant and growing cause of death and disability worldwide, involves
inflammation from its inception to the emergence of complications. Targeting inflammatory …

Abstract Treatment of acute lung injury (ALI) and its most severe form, acute respiratory distress
syndrome (ARDS), remain unsolved problems of intensive care medicine. ALI/ARDS are …

Neutrophils, monocytes and macrophages are closely related phagocytic cells that cooperate
during the onset, progression and resolution of inflammation. This Review highlights the …

Resolution of inflammation is a coordinated and active process aimed at restoration of tissue
integrity and function. This review integrates the key molecular and cellular mechanisms of …

Background— Inflammation and activation of immune cells are key mechanisms in the
development of atherosclerosis. Previous data indicate important roles for monocytes and T …

Aims Acute myocardial infarction (MI) is the leading cause of mortality worldwide. Anti-inflammatory
strategies to reduce neutrophil-driven acute post-MI injury have been shown to limit …

Clonal haematopoiesis, which is highly prevalent in older individuals, arises from somatic
mutations that endow a proliferative advantage to haematopoietic cells. Clonal …

Because of their rare detection in atherosclerotic lesions, the involvement of neutrophils in
the pathophysiology of atherosclerosis has been largely denied. However, over the past …

The leukocyte response in inflammation is characterized by an initial recruitment of
polymorphonuclear leukocytes (PMN) preceding a second wave of monocytes to the site of injury or …