When laser light illuminates a diffuse object, it produces a random interference effect known
as a speckle pattern. If there is movement in the object, the speckles fluctuate in intensity. …

Background and Aims Anaemia is a major health burden worldwide. Although the finding of
conjunctival pallor on clinical examination is associated with anaemia, inter-observer …

Defects in neural crest development have been implicated in many human disorders, but
information about human neural crest formation mostly depends on extrapolation from model …

10.7554/eLife.35786.001 The neural crest (NC) is a multipotent embryonic cell population that
generates distinct cell types in an axial position-dependent manner. The production of NC …

The occurrence of repetitive genomic changes that provide a selective growth advantage in
pluripotent stem cells is of concern for their clinical application. However, the effect of …

Variations in skin perfusion are easily detected by laser speckle contrast maps, but a robust
interpretation of the information has been lacking. We show that multiple-exposure laser …

Practical laser speckle contrast analysis systems face a problem of spatial averaging of
speckles, due to the pixel size in the cameras used. Existing practice is to use a system factor in …

A group of diverse proteins reversibly binds to growing microtubule plus ends through
interactions with end-binding proteins (EBs). These +TIPs control microtubule dynamics and …

Background SM22 has long been studied as an actin-associated protein. Interestingly,
levels of SM22 are often reduced in tumour cell lines, while they are increased during …

10.7554/eLife.47678.001 Prostate is the most frequent cancer in men. Prostate cancer
progression is driven by androgen steroid hormones, and delayed by androgen deprivation …