First 12 patients with coronavirus disease 2019 (COVID-19) in the United States

…, M Marlow, GE Mathisen, N McClung, O McGovern… - MedRxiv, 2020 - medrxiv.org
Introduction More than 93,000 cases of coronavirus disease (COVID-19) have been reported
worldwide. We describe the epidemiology, clinical course, and virologic characteristics of …

Toxoplasma gondii ingests and digests host cytosolic proteins

Z Dou, OL McGovern, M Di Cristina, VB Carruthers - MBio, 2014 - Am Soc Microbiol
The protozoan parasite Toxoplasma gondii resides within a nonfusogenic vacuole during
intracellular replication. Although the limiting membrane of this vacuole provides a protective …

Toxoplasma depends on lysosomal consumption of autophagosomes for persistent infection

…, M Lunghi, G Kannan, MH Huynh, OL McGovern… - Nature …, 2017 - nature.com
Globally, nearly 2 billion people are infected with the intracellular protozoan Toxoplasma
gondii 1. This persistent infection can cause severe disease in immunocompromised people …

[HTML][HTML] Psittacosis outbreak among workers at chicken slaughter plants, Virginia and Georgia, USA, 2018

…, A Kunkes, M Davis, OL McGovern… - Emerging infectious …, 2019 - ncbi.nlm.nih.gov
During August–October, 2018, an outbreak of severe respiratory illness was reported among
poultry slaughter plant workers in Virginia and Georgia, USA. A multiorganizational team …

Crossover Distribution and Frequency Are Regulated by him-5 in Caenorhabditis elegans

PM Meneely, OL McGovern, FI Heinis, JL Yanowitz - Genetics, 2012 - academic.oup.com
Mutations in the him-5 gene in Caenorhabditis elegans strongly reduce the frequency of
crossovers on the X chromosome, with lesser effects on the autosomes. him-5 mutants also …

Intersection of endocytic and exocytic systems in Toxoplasma gondii

OL McGovern, Y Rivera‐Cuevas, G Kannan… - Traffic, 2018 - Wiley Online Library
Host cytosolic proteins are endocytosed by Toxoplasma gondii and degraded in its
lysosome‐like compartment, the vacuolar compartment (VAC), but the dynamics and route of …

[PDF][PDF] A surveillance system ensures crossover formation in C. elegans

TS Machovina, R Mainpal, A Daryabeigi, O McGovern… - Current Biology, 2016 - cell.com
Crossover (CO) recombination creates a physical connection between homologs that
promotes their proper segregation at meiosis I (MI). Failure to realize an obligate CO causes …

Prescribing of outpatient antibiotics commonly used for respiratory infections among adults before and during the coronavirus disease 2019 pandemic in Brazil

D Solanky, OL McGovern, JR Edwards… - Clinical Infectious …, 2023 - academic.oup.com
Background The coronavirus disease 2019 (COVID-19) pandemic may have impacted
outpatient antibiotic prescribing in low- and middle-income countries such as Brazil. However, …

Calcium sensing receptor mutations implicated in pancreatitis and idiopathic epilepsy syndrome disrupt an arginine-rich retention motif

A Stepanchick, J McKenna, O McGovern… - Cellular Physiology and …, 2010 - karger.com
Calcium sensing receptor (CaSR) mutations implicated in familial hypocalciuric hypercalcemia,
pancreatitis and idiopathic epilepsy syndrome map to an extended arginine-rich region …

[HTML][HTML] Use of real-time PCR for Chlamydia psittaci detection in human specimens during an outbreak of psittacosis—Georgia and Virginia, 2018

OL McGovern - MMWR. Morbidity and Mortality Weekly Report, 2021 - cdc.gov
Real-time polymerase chain reaction (PCR) testing for Chlamydia psittaci, the bacterium
that causes psittacosis, is faster and more specific than widely available serologic tests. …