User profiles for Olivier Gascuel

Olivier Gascuel

CNRS & Muséum National d'Histoire Naturelle
Verified email at mnhn.fr
Cited by 71041

New algorithms and methods to estimate maximum-likelihood phylogenies: assessing the performance of PhyML 3.0

…, V Lefort, M Anisimova, W Hordijk, O Gascuel - Systematic …, 2010 - academic.oup.com
PhyML is a phylogeny software based on the maximum-likelihood principle. Early PhyML
versions used a fast algorithm performing nearest neighbor interchanges to improve a …

SeaView version 4: a multiplatform graphical user interface for sequence alignment and phylogenetic tree building

M Gouy, S Guindon, O Gascuel - Molecular biology and …, 2010 - academic.oup.com
We present SeaView version 4, a multiplatform program designed to facilitate multiple
alignment and phylogenetic tree building from molecular sequence data through the use of a …

A simple, fast, and accurate algorithm to estimate large phylogenies by maximum likelihood

S Guindon, O Gascuel - Systematic biology, 2003 - academic.oup.com
The increase in the number of large data sets and the complexity of current probabilistic
sequence evolution models necessitates fast and reliable phylogeny reconstruction methods. …

Phylogeny. fr: robust phylogenetic analysis for the non-specialist

…, V Lefort, M Lescot, JM Claverie, O Gascuel - Nucleic acids …, 2008 - academic.oup.com
Phylogenetic analyses are central to many research areas in biology and typically involve
the identification of homologous sequences, their multiple alignment, the phylogenetic …

Approximate likelihood-ratio test for branches: a fast, accurate, and powerful alternative

M Anisimova, O Gascuel - Systematic biology, 2006 - academic.oup.com
We revisit statistical tests for branches of evolutionary trees reconstructed upon molecular
data. A new, fast, approximate likelihood-ratio test (aLRT) for branches is presented here as a …

An improved general amino acid replacement matrix

SQ Le, O Gascuel - Molecular biology and evolution, 2008 - academic.oup.com
Amino acid replacement matrices are an essential basis of protein phylogenetics. They are
used to compute substitution probabilities along phylogeny branches and thus the likelihood …

BIONJ: an improved version of the NJ algorithm based on a simple model of sequence data.

O Gascuel - Molecular biology and evolution, 1997 - academic.oup.com
We propose an improved version of the neighbor-joining (NJ) algorithm of Saitou and Nei.
This new algorithm, BIONJ, follows the same agglomerative scheme as NJ, which consists of …

SMS: smart model selection in PhyML

…, JE Longueville, O Gascuel - Molecular biology and …, 2017 - academic.oup.com
Abstract Model selection using likelihood-based criteria (eg, AIC) is one of the first steps in
phylogenetic analysis. One must select both a substitution matrix and a model for rates across …

PHYML Online—a web server for fast maximum likelihood-based phylogenetic inference

…, F Lethiec, P Duroux, O Gascuel - Nucleic acids …, 2005 - academic.oup.com
PHYML Online is a web interface to PHYML, a software that implements a fast and accurate
heuristic for estimating maximum likelihood phylogenies from DNA and protein sequences. …

FastME 2.0: a comprehensive, accurate, and fast distance-based phylogeny inference program

V Lefort, R Desper, O Gascuel - Molecular biology and evolution, 2015 - academic.oup.com
FastME provides distance algorithms to infer phylogenies. FastME is based on balanced
minimum evolution, which is the very principle of Neighbor Joining (NJ). FastME improves over …