User profiles for Olivier Giannini

Olivier Giannini

Department of Medicine, Ente Ospedaliero Cantonale, Bellinzona
Verified email at eoc.ch
Cited by 2467

[HTML][HTML] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift

…, R Grifantini, H Chu, A Gori, A Riva, O Giannini… - Nature, 2022 - nature.com
The recently emerged SARS-CoV-2 Omicron variant encodes 37 amino acid substitutions in
the spike protein, 15 of which are in the receptor-binding domain (RBD), thereby raising …

Broad betacoronavirus neutralization by a stem helix–specific human antibody

…, A Cassotta, A Ceschi, P Ferrari, PE Cippà, O Giannini… - Science, 2021 - science.org
The spillovers of betacoronaviruses in humans and the emergence of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) variants highlight the need for broad coronavirus …

Imprinted antibody responses against SARS-CoV-2 Omicron sublineages

…, R Abdelnabi, P Maes, P Ferrari, A Ceschi, O Giannini… - Science, 2022 - science.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry
distinct spike mutations resulting in escape from antibodies induced by previous infection or …

[HTML][HTML] Neutralization, effector function and immune imprinting of Omicron variants

…, F Larrous, E Cameroni, B Whitener, O Giannini… - Nature, 2023 - nature.com
Currently circulating SARS-CoV-2 variants have acquired convergent mutations at hot spots
in the receptor-binding domain 1 (RBD) of the spike protein. The effects of these mutations …

[HTML][HTML] Risk assessment and seroprevalence of SARS-CoV-2 infection in healthcare workers of COVID-19 and non-COVID-19 hospitals in Southern Switzerland

…, A Lanzavecchia, C Garzoni, O Giannini… - The Lancet Regional …, 2021 - thelancet.com
Background Hospital healthcare workers (HCW), in particular those involved in the clinical
care of COVID-19 cases, are presumably exposed to a higher risk of acquiring the disease …

[HTML][HTML] Frequency and severity of pain and symptom distress among patients with chronic kidney disease receiving dialysis

…, G Bianchi, C Ferrier, C Cereghetti, O Giannini - Swiss medical …, 2013 - smw.ch
QUESTION UNDER STUDY: Data on pain management in haemodialysis patients with end-stage
renal disease are scanty. Our study aimed to collect information on the frequency and …

[HTML][HTML] Poor neutralization and rapid decay of antibodies to SARS-CoV-2 variants in vaccinated dialysis patients

J Bassi, O Giannini, C Silacci-Fregni, L Pertusini… - PLoS …, 2022 - journals.plos.org
Patients on dialysis are at risk of severe course of SARS-CoV-2 infection. Understanding the
neutralizing activity and coverage of SARS-CoV-2 variants of vaccine-elicited antibodies is …

Therapeutic and vaccine-induced cross-reactive antibodies with effector function against emerging Omicron variants

…, FA Lempp, E Cameroni, B Whitener, O Giannini… - Biorxiv, 2023 - biorxiv.org
Currently circulating SARS-CoV-2 variants acquired convergent mutations at receptor-binding
domain (RBD) hot spots 1 . Their impact on viral infection, transmission, and efficacy of …

[HTML][HTML] The great fluid debate: saline or so-called “balanced” salt solutions?

M Santi, SAG Lava, P Camozzi, O Giannini… - Italian journal of …, 2015 - Springer
Background Intravenous fluids are commonly prescribed in childhood. 0.9 % saline is the
most-used fluid in pediatrics as resuscitation or maintenance solution. Experimental studies …

Prevalence, clinical relevance and predictive factors of medication discrepancies revealed by medication reconciliation at hospital admission: prospective study in a …

O Giannini, N Rizza, M Pironi, S Parlato, BW Suter… - BMJ open, 2019 - bmjopen.bmj.com
Objective Medication reconciliation (MedRec) is a relevant safety procedure in medication
management at transitions of care. The aim of this study was to evaluate the impact of MedRec…