Neuronal pattern separation is thought to enable the brain to disambiguate sensory stimuli
with overlapping features, thereby extracting valuable information. In the olfactory system, it …

In mammals, odorant molecules are thought to activate only a few glomeruli, leading to the
hypothesis that odor representation in the olfactory bulb is sparse. However, the studies …

Background How do neural networks encode sensory information? Following sensory
stimulation, neural coding is commonly assumed to be based on neurons changing their firing rate…

In sensory systems, peripheral organs convey sensory inputs to relay networks where
information is shaped by local microcircuits before being transmitted to cortical areas. In the …

In various mental disorders, dysfunction of the prefrontal cortex contributes to cognitive deficits.
Here we studied how the claustrum (CLA), a nucleus sharing reciprocal connections with …

Sensory information undergoes substantial transformation along sensory pathways, usually
encompassing sparsening of activity. In the olfactory bulb, though natural odorants evoke …

Knowledge about the molecular organization principles of the sense of smell in different
species has greatly improved in the last decade (Bargmann 2006; Mombaerts 2004a, 2004b; …

Synaptic inhibition in the olfactory bulb (OB), the first relay station of olfactory information, is
believed to be important for odour discrimination. We interfered with GABAergic inhibition of …

The rules governing behavior often vary with behavioral contexts. As a consequence, an
action rewarded in one context may be discouraged in another. Animals and humans are …

Neuronal pattern separation is thought to enable the brain to disambiguate sensory stimuli
with overlapping features, thereby extracting valuable information. In the olfactory system, it …