In silico molecular modeling and simulations of black tea theaflavins revealed theaflavin-3'-gallate as putative liver X receptor-beta agonist
…, OS Omotayo, OA Medayedupin - Journal of …, 2023 - Taylor & Francis
The low constitutive activation of Liver X receptor, an endogenous nuclear receptor with two
subtypes (α and β), is a condition lying at the crossroad of cancer and cardiovascular …
subtypes (α and β), is a condition lying at the crossroad of cancer and cardiovascular …
Toxicity assessment of 3–O–[6–deoxy–3–O–methyl–β–D–allopyranosyl–(1→ 4)–β–D–oleandropyranosyl]–17β–marsdenin isolated from Gongronema latifolium leaf …
OG Ani, OA Medayedupin, AA Azeez, GA Gyebi… - bioRxiv, 2024 - biorxiv.org
The safety of bioactive compounds, especially those isolated from medicinal plants, is a major
concern for health authorities, pharmaceutical industries, and the public. Of recent, anti–…
concern for health authorities, pharmaceutical industries, and the public. Of recent, anti–…
Discovery of Eriodictyol as Putative Exportin-1 Inhibitor for Non-small Cell Lung Cancer Therapy
…, IY Joel, OO Bankole, GO Ambrose, OA Medayedupin… - 2020 - preprints.org
Exportin-1, the ubiquitous nuclear protein transporter, is widely confirmed as an active
chemotherapeutic target in non-small cell lung cancer condition while Juglans mandshurica is a …
chemotherapeutic target in non-small cell lung cancer condition while Juglans mandshurica is a …
Selection Of Theaflavin 2B As a Potential HSP90 Antagonist Semi-rigid Ligand Docking Analysis
S Akinsehinwa, O Medayedupin - bioRxiv, 2022 - biorxiv.org
Heat shock protein 90 (HSP90) is an abundant molecular chaperone playing critical role as
mediator of proper folding, maturation and stability of diverse client cellular proteins and has …
mediator of proper folding, maturation and stability of diverse client cellular proteins and has …
Tackling the Moving Mutant Target: Taxifolin Derivatives as Novel Putative E571K Exportin-1 Inhibitors for KRAS-mutant Lung Adenocarcinoma Therapy
T Adigun, O Medayedupin, I Joel, I Fakolujo… - 2020 - preprints.org
Aim: To establish, through molecular modelling, safe and clinically acceptable putative
antagonists of E571K-mutated exportin-1 among the bioactive compounds in various parts of …
antagonists of E571K-mutated exportin-1 among the bioactive compounds in various parts of …
[PDF][PDF] In silico molecular modeling and simulations of black tea theaflavins revealed theaflavin-3'-gallate as putative liver X receptor-beta agonist
The low constitutive activation of Liver X receptor, an endogenous nuclear receptor with two
subtypes (a and b), is a condition lying at the crossroad of cancer and cardiovascular …
subtypes (a and b), is a condition lying at the crossroad of cancer and cardiovascular …