Chemical descriptors encode the physicochemical and structural properties of small molecules,
and they are at the core of chemoinformatics. The broad release of bioactivity data has …

Small molecules are usually compared by their chemical structure, but there is no unified
analytic framework for representing and comparing their biological activity. We present the …

The Columbia Cancer Target Discovery and Development (CTD2) Center is developing
PANACEA, a resource comprising dose-responses and RNA sequencing (RNA-seq) profiles of …

Motivation Most computational approaches for the analysis of omics data in the context of
interaction networks have very long running times, provide single or partial, often heuristic, …

Biological processes often manifest themselves as coordinated changes across modules, ie,
sets of interacting genes. Commonly, the high dimensionality of genome-scale data …

We describe a blind watermarking technique for digital images. Our technique constructs an
image-dependent watermark in the discrete wavelet transform (DWT) domain and inserts …

Motivation: Research on methods for the inference of networks from biological data is making
significant advances, but the adoption of network inference in biomedical research practice …

Background The widespread incorporation of next-generation sequencing into clinical oncology
has yielded an unprecedented amount of molecular data from thousands of patients. A …

As a network visualization and analysis platform, Cytoscape relies on apps to provide
domain-specific features and functions. There are many resources available to support Cytoscape …

Until a vaccine becomes available, the current repertoire of drugs is our only therapeutic asset
to fight the SARS-CoV-2 outbreak. Indeed, emergency clinical trials have been launched …