Macrophages are key players during Paracoccidioides brasiliensis infection. However, the
relative contribution of the fungal response to counteracting macrophage activity remains …

The ability of Paracoccidioides to defend itself against reactive oxygen species (ROS)
produced by host effector cells is a prerequisite to survive. To counteract these radicals, …

Iron is essential for the proliferation of fungal pathogens during infection. The availability of
iron is limited due to its association with host proteins. Fungal pathogens have evolved …

Neutrophils play an important role as effector cells and contribute to the resistance of the host
against microbial pathogens. Neutrophils are able to produce extracellular traps (NETs) in …

Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with Paracoccidioides
brasiliensis and P. lutzii being the causal agents of this disorder. Several issues have …

One of the most crucial events during infection with the dimorphic fungus Paracoccidioides
brasiliensis is adhesion to pulmonary epithelial cells, a pivotal step in the establishment of …

Glycoprotein gp43 is an immunodominant diagnostic antigen for paracoccidioidomycosis
caused by Paracoccidioides brasiliensis. It is abundantly secreted in isolates such as Pb339. It …

HSP90 is a molecular chaperone that participates in folding, stabilization, activation, and
assembly of several proteins, all of which are key regulators in cell signaling. In dimorphic …

The fungus Paracoccidioides is a prevalent human pathogen endemic to South America. The
genus is composed of five species. In this report, we use 37 whole-genome sequences to …

Microorganisms adhere to extracellular matrix proteins by means of their own surface
molecules. Paracoccidioides brasiliensis conidia have been shown to be capable of interacting …