User profiles for Osamu Komagata
 | Osamu KOMAGATADepartment of Medical Entomology, National Institute of Infectious Diseases Verified email at niid.go.jp Cited by 2319 |
[HTML][HTML] Mechanisms of Pyrethroid Resistance in the Dengue Mosquito Vector, Aedes aegypti: Target Site Insensitivity, Penetration, and Metabolism
Aedes aegypti is the major vector of yellow and dengue fevers. After 10 generations of adult
selection, an A. aegypti strain (SP) developed 1650-fold resistance to permethrin, which is …
selection, an A. aegypti strain (SP) developed 1650-fold resistance to permethrin, which is …
[HTML][HTML] Widespread Distribution of a Newly Found Point Mutation in Voltage-Gated Sodium Channel in Pyrethroid-Resistant Aedes aegypti Populations in Vietnam
H Kawada, Y Higa, O Komagata, S Kasai… - PLoS neglected …, 2009 - journals.plos.org
Background Resistance of Aedes aegypti to photostable pyrethroid insecticides is a major
problem for disease-vector control programs. Pyrethroids target the voltage-gated sodium …
problem for disease-vector control programs. Pyrethroids target the voltage-gated sodium …
First detection of a putative knockdown resistance gene in major mosquito vector, Aedes albopictus
…, CS Tang, K Itokawa, O Komagata… - Japanese journal of …, 2011 - jstage.jst.go.jp
The Asian tiger mosquito, Aedes albopictus (Skuse), is the major vector of Chikungunya
fever and the secondary vector of dengue fever. We collected Ae. albopictus from Singapore …
fever and the secondary vector of dengue fever. We collected Ae. albopictus from Singapore …
[HTML][HTML] A Single Crossing-Over Event in Voltage-Sensitive Na+ Channel Genes May Cause Critical Failure of Dengue Mosquito Control by Insecticides
K Hirata, O Komagata, K Itokawa… - PLoS neglected …, 2014 - journals.plos.org
The voltage-sensitive sodium (Na + ) channel (Vssc) is the target site of pyrethroid
insecticides. Pest insects develop resistance to this class of insecticide by acquisition of one or …
insecticides. Pest insects develop resistance to this class of insecticide by acquisition of one or …
Overexpression of cytochrome P450 genes in pyrethroid-resistant Culex quinquefasciatus
O Komagata, S Kasai, T Tomita - Insect biochemistry and molecular biology, 2010 - Elsevier
JPal-per strain of Culex quinquefasciatus exhibits extremely high resistance against
pyrethroids in larvae, though the resistance is greatly lower in adults. Increased microsome …
pyrethroids in larvae, though the resistance is greatly lower in adults. Increased microsome …
[HTML][HTML] Multimodal Pyrethroid Resistance in Malaria Vectors, Anopheles gambiae ss, Anopheles arabiensis, and Anopheles funestus ss in Western Kenya
Anopheles gambiae ss, Anopheles arabiensis, and Anopheles funestus ss are the most
important species for malaria transmission. Pyrethroid resistance of these vector mosquitoes is …
important species for malaria transmission. Pyrethroid resistance of these vector mosquitoes is …
[HTML][HTML] Testing the causality between CYP9M10 and pyrethroid resistance using the TALEN and CRISPR/Cas9 technologies
Recently-emerging genome editing technologies have enabled targeted gene knockout
experiments even in non-model insect species. For studies on insecticide resistance, genome …
experiments even in non-model insect species. For studies on insecticide resistance, genome …
[HTML][HTML] First detection of a Vssc allele V1016G conferring a high level of insecticide resistance in Aedes albopictus collected from Europe (Italy) and Asia (Vietnam) …
…, V Pichler, K Itokawa, K Murota, O Komagata… - …, 2019 - eurosurveillance.org
Introduction Aedes albopictus (Skuse) is an important vector of arboviral diseases, including
dengue, chikungunya and Zika virus disease. Monitoring insecticide resistance and …
dengue, chikungunya and Zika virus disease. Monitoring insecticide resistance and …
Genomic structures of Cyp9m10 in pyrethroid resistant and susceptible strains of Culex quinquefasciatus
Development of insecticide resistance reduces the efficacy of controlling measures against
the medical and agricultural insect pests. Cytochrome P450s are one of the major …
the medical and agricultural insect pests. Cytochrome P450s are one of the major …
Discovery of super–insecticide-resistant dengue mosquitoes in Asia: Threats of concomitant knockdown resistance mutations
…, KC Mulyatno, K Sawabe, T Tomita, O Komagata - Science …, 2022 - science.org
Aedes aegypti (Linnaeus, 1762) is the main mosquito vector for dengue and other arboviral
infectious diseases. Control of this important vector highly relies on the use of insecticides, …
infectious diseases. Control of this important vector highly relies on the use of insecticides, …