User profiles for Oscar P. B. Wiklander
Oscar PB WiklanderSenior researcher, Karolinska institutet Verified email at ki.se Cited by 4677 |
Extracellular vesicle in vivo biodistribution is determined by cell source, route of administration and targeting
OPB Wiklander, JZ Nordin, A O'Loughlin… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs) have emerged as important mediators of intercellular communication
in a diverse range of biological processes. For future therapeutic applications and for …
in a diverse range of biological processes. For future therapeutic applications and for …
Advances in therapeutic applications of extracellular vesicles
Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles secreted
by most, if not all, cells and contain lipids, proteins, and various nucleic acid species of …
by most, if not all, cells and contain lipids, proteins, and various nucleic acid species of …
[HTML][HTML] Ultrafiltration with size-exclusion liquid chromatography for high yield isolation of extracellular vesicles preserving intact biophysical and functional properties
…, HJ Johansson, W Heusermann, OPB Wiklander… - … , Biology and Medicine, 2015 - Elsevier
Extracellular vesicles (EVs) are natural nanoparticles that mediate intercellular transfer of
RNA and proteins and are of great medical interest; serving as novel biomarkers and potential …
RNA and proteins and are of great medical interest; serving as novel biomarkers and potential …
Identification of storage conditions stabilizing extracellular vesicles preparations
…, DW Hagey, R Jawad Wiklander… - Journal of …, 2022 - Wiley Online Library
Extracellular vesicles (EVs) play a key role in many physiological and pathophysiological
processes and hold great potential for therapeutic and diagnostic use. Despite significant …
processes and hold great potential for therapeutic and diagnostic use. Despite significant …
[HTML][HTML] Systematic methodological evaluation of a multiplex bead-based flow cytometry assay for detection of extracellular vesicle surface signatures
OPB Wiklander, RB Bostancioglu, JA Welsh… - Frontiers in …, 2018 - frontiersin.org
Extracellular vesicles (EVs) can be harvested from cell culture supernatants and from all
body fluids. EVs can be conceptually classified based on their size and biogenesis as …
body fluids. EVs can be conceptually classified based on their size and biogenesis as …
In vivo effects of mesenchymal stromal cells in two patients with severe acute respiratory distress syndrome
…, S El Andaloussi, OPB Wiklander… - Stem cells …, 2015 - academic.oup.com
This article describes the cases of two patients with severe refractory adult respiratory
syndrome (ARDS) who failed to improve after both standard life support measures, including …
syndrome (ARDS) who failed to improve after both standard life support measures, including …
[HTML][HTML] Exosomes participate in the alteration of muscle homeostasis during lipid-induced insulin resistance in mice
H Aswad, A Forterre, OPB Wiklander, G Vial… - Diabetologia, 2014 - Springer
Aims/hypothesis Exosomes released from cells can transfer both functional proteins and
RNAs between cells. In this study we tested the hypothesis that muscle cells might transmit …
RNAs between cells. In this study we tested the hypothesis that muscle cells might transmit …
Serum-free culture alters the quantity and protein composition of neuroblastoma-derived extracellular vesicles
…, P Vader, JZ Nordin, OPB Wiklander… - Journal of …, 2015 - Taylor & Francis
Extracellular vesicles (EVs) play a significant role in cell–cell communication in numerous
physiological processes and pathological conditions, and offer promise as novel biomarkers …
physiological processes and pathological conditions, and offer promise as novel biomarkers …
[HTML][HTML] Exosome-like vesicles released from lipid-induced insulin-resistant muscles modulate gene expression and proliferation of beta recipient cells in mice
A Jalabert, G Vial, C Guay, OPB Wiklander, JZ Nordin… - Diabetologia, 2016 - Springer
Aims/hypothesis The crosstalk between skeletal muscle (SkM) and beta cells plays a role in
diabetes aetiology. In this study, we have investigated whether SkM-released exosome-like …
diabetes aetiology. In this study, we have investigated whether SkM-released exosome-like …
[HTML][HTML] Heterogeneity and interplay of the extracellular vesicle small RNA transcriptome and proteome
…, HJ Johansson, JZ Nordin, OPB Wiklander… - Scientific reports, 2018 - nature.com
Extracellular vesicles (EVs) mediate cell-to-cell communication by delivering or displaying
macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their …
macromolecules to their recipient cells. While certain broad-spectrum EV effects reflect their …