User profiles for Osvaldo D. Rivera
 | Osvaldo D. Rivera-González, PhDPrincipal Scientist, RIVERA-OMICS Verified email at riveraomics.org Cited by 123 |
Alternative splicing redefines landscape of commonly mutated genes in acute myeloid leukemia
OD Rivera, MJ Mallory… - Proceedings of the …, 2021 - National Acad Sciences
Most genes associated with acute myeloid leukemia (AML) are mutated in less than 10% of
patients, suggesting that alternative mechanisms of gene disruption contribute to this disease…
patients, suggesting that alternative mechanisms of gene disruption contribute to this disease…
[HTML][HTML] Tyrosine phosphorylation of the orphan receptor ESDN/DCBLD2 serves as a scaffold for the signaling adaptor CrkL
A quantitative proteomics screen to identify substrates of the Src family of tyrosine kinases (SFKs)
whose phosphorylation promotes CrkL-SH2 binding identified the known Crk-…
whose phosphorylation promotes CrkL-SH2 binding identified the known Crk-…
[HTML][HTML] Parkin deficiency suppresses antigen presentation to promote tumor immune evasion and immunotherapy resistance
Parkin prevents immune evasion by regulating tumor antigen processing and presentation
through the PTEN/Akt network, which has important implications for immunotherapy …
through the PTEN/Akt network, which has important implications for immunotherapy …
Kinetic analysis of the exonuclease activity of the bacteriophage T4 Mre11–Rad50 complex
Bacteriophage T4 encodes orthologs of the proteins Rad50 (gp46) and Mre11 (gp47), which
form a heterotetrameric complex (MR) that is responsible for host genome degradation and …
form a heterotetrameric complex (MR) that is responsible for host genome degradation and …
Alternative mRNA Splicing Redefines the Landscape of Commonly Dysregulated Genes Across the Acute Myeloid Leukemia Patient Population
OD Rivera - 2021 - search.proquest.com
Most genes associated with acute myeloid leukemia (AML) are mutated in less than 10% of
patients, suggesting that alternative mechanisms of gene disruption contribute to this disease…
patients, suggesting that alternative mechanisms of gene disruption contribute to this disease…
[HTML][HTML] Efficacy of a tetravalent dengue vaccine in children in Latin America
…, JL Arredondo-García, DM Rivera… - … England Journal of …, 2015 - Mass Medical Soc
Background In light of the increasing rate of dengue infections throughout the world despite
vector-control measures, several dengue vaccine candidates are in development. Methods …
vector-control measures, several dengue vaccine candidates are in development. Methods …
[PDF][PDF] Genome-wide identification of structure-forming repeats as principal sites of fork collapse upon ATR inhibition
DNA polymerase stalling activates the ATR checkpoint kinase, which in turn suppresses
fork collapse and breakage. Herein, we describe use of ATR inhibition (ATRi) as a means to …
fork collapse and breakage. Herein, we describe use of ATR inhibition (ATRi) as a means to …
[HTML][HTML] Mapping macrophage polarization over the myocardial infarction time continuum
…, KY DeLeon-Pennell, OJ Rivera Gonzalez… - Basic research in …, 2018 - Springer
In response to myocardial infarction (MI), cardiac macrophages regulate inflammation and
scar formation. We hypothesized that macrophages undergo polarization state changes over …
scar formation. We hypothesized that macrophages undergo polarization state changes over …
Myocardial infarction remodeling that progresses to heart failure: a signaling misunderstanding
AJ Mouton, OJ Rivera… - American Journal of …, 2018 - journals.physiology.org
After myocardial infarction, remodeling of the left ventricle involves a wound-healing orchestra
involving a variety of cell types. In order for wound healing to be optimal, appropriate …
involving a variety of cell types. In order for wound healing to be optimal, appropriate …
β− Arrestins: structure, function, physiology, and pharmacological perspectives
The two β-arrestins, β-arrestin-1 and -2 (systematic names: arrestin-2 and -3, respectively),
are multifunctional intracellular proteins that regulate the activity of a very large number of …
are multifunctional intracellular proteins that regulate the activity of a very large number of …