User profiles for Ouardia Ait Mohamed

ouardia ait-mohamed

Enseignante, Université de Sorbonne Paris Nord
Verified email at univ-paris13.fr
Cited by 13417

Hypometabolism to survive the long polar night and subsequent successful return to light in the diatom Fragilariopsis cylindrus

…, T Sciandra, F Bruyant, O AitMohamed… - New …, 2024 - Wiley Online Library
Diatoms, the main eukaryotic phytoplankton of the polar marine regions, are essential for
the maintenance of food chains specific to Arctic and Antarctic ecosystems, and are …

DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

…, S Drevensek, S Fonseca, E Iniesto, O Ait-Mohamed… - Elife, 2018 - elifesciences.org
10.7554/eLife.37892.001 DE-ETIOLATED 1 (DET1) is an evolutionarily conserved component
of the ubiquitination machinery that mediates the destabilization of key regulators of cell …

Phylogenomic fingerprinting of tempo and functions of horizontal gene transfer within ochrophytes

…, AK Watson, O Ait-Mohamed… - Proceedings of the …, 2021 - National Acad Sciences
Horizontal gene transfer (HGT) is an important source of novelty in eukaryotic genomes.
This is particularly true for the ochrophytes, a diverse and important group of algae. Previous …

[HTML][HTML] PhaeoNet: A Holistic RNAseq-Based Portrait of Transcriptional Coordination in the Model Diatom Phaeodactylum tricornutum

O Ait-Mohamed, AMG Novák Vanclová, N Joli… - Frontiers in Plant …, 2020 - frontiersin.org
Transcriptional coordination is a fundamental component of prokaryotic and eukaryotic cell
biology, underpinning the cell cycle, physiological transitions, and facilitating holistic …

[HTML][HTML] Acetonic Extract of Buxus sempervirens Induces Cell Cycle Arrest, Apoptosis and Autophagy in Breast Cancer Cells

O Ait-Mohamed, V Battisti, V Joliot, L Fritsch, J Pontis… - PloS one, 2011 - journals.plos.org
Plants are an invaluable source of potential new anti-cancer drugs. Here, we investigated
the cytotoxic activity of the acetonic extract of Buxus sempervirens on five breast cancer cell …

Genome wide natural variation of H3K27me3 selectively marks genes predicted to be important for cell differentiation in Phaeodactylum tricornutum

…, AF Deton Cabanillas, O Ait Mohamed… - New …, 2021 - Wiley Online Library
In multicellular organisms, Polycomb Repressive Complex2 (PRC2) is known to deposit tri‐methylation
of lysine 27 of histone H3 (H3K27me3) to establish and maintain gene silencing, …

[HTML][HTML] The model diatom Phaeodactylum tricornutum provides insights into the diversity and function of microeukaryotic DNA methyltransferases

…, C Bowler, A Genovesio, O Ait-Mohamed… - Communications …, 2023 - nature.com
Cytosine methylation is an important epigenetic mark involved in the transcriptional control
of transposable elements in mammals, plants and fungi. The Stramenopiles-Alveolate-…

The plant POLYMERASE-ASSOCIATED FACTOR1 complex links transcription and H2B monoubiquitination genome wide

…, C Bourbousse, D Latrasse, O Ait-Mohamed… - Plant …, 2024 - academic.oup.com
The evolutionarily conserved POLYMERASE ASSOCIATED FACTOR1 complex (Paf1C)
participates in transcription, and research in animals and fungi suggests that it facilitates RNA …

[HTML][HTML] The SWI/SNF subunit/tumor suppressor BAF47/INI1 is essential in cell cycle arrest upon skeletal muscle terminal differentiation

V Joliot, O Ait-Mohamed, V Battisti, J Pontis, O Philipot… - PloS one, 2014 - journals.plos.org
Myogenic terminal differentiation is a well-orchestrated process starting with permanent cell
cycle exit followed by muscle-specific genetic program activation. Individual SWI/SNF …

[HTML][HTML] The core binding factor CBF negatively regulates skeletal muscle terminal differentiation

O Philipot, V Joliot, O Ait-Mohamed, C Pellentz… - PloS one, 2010 - journals.plos.org
Background Core Binding Factor or CBF is a transcription factor composed of two subunits,
Runx1/AML-1 and CBF beta or CBFβ. CBF was originally described as a regulator of …