Helminth endemic regions report lower COVID-19 morbidity and mortality. Here, we show
that lung remodeling from a prior infection with a lung-migrating helminth, Nippostrongylus …

Type 2 inflammation is associated with epithelial cell responses, including goblet cell hyperplasia,
that promote worm expulsion during intestinal helminth infection. How these epithelial …

Canine parvovirus (CPV) is a highly successful pathogen that has sustained pandemic
circulation in dogs for more than 40 years. Here, integrating full-genome and deep-sequencing …

Helminths have evolved sophisticated immune regulating mechanisms to prevent rejection
by their mammalian host. Our understanding of how the human immune system responds to …

Group 2 innate lymphoid cells (ILC2s) are rare innate immune cells that accumulate in tissues
during allergy and helminth infection, performing critical effector functions that drive type 2 …

It is of great interest to understand how invading pathogens are sensed within the brain, a
tissue with unique challenges to mounting an immune response. The eukaryotic parasite …

Type 2 immunity is critical for the protective and repair responses that mediate resistance to
parasitic helminth infection. This immune response also drives aberrant inflammation during …

Type 2 inflammation drives the clearance of gastrointestinal helminth parasites, which infect
over two billion people worldwide. Basophils are innate immune cells that support host-…

Helminth infection currently affect over 2 billion people worldwide, with those with the most
pathologies and morbidities, living in regions with unequal and disproportionate access to …

CD8 + T cells are classically recognized as adaptive lymphocytes based on their ability to
recognize specific foreign antigens and mount memory responses. However, recent studies …