User profiles for P Wappner
 | Pablo WappnerInstituto Leloir Verified email at leloir.org.ar Cited by 15755 |
Sensing and responding to hypoxia via HIF in model invertebrates
TA Gorr, M Gassmann, P Wappner - Journal of insect physiology, 2006 - Elsevier
This past decade has brought considerable progress towards elucidating the molecular
mechanisms of oxygen sensing pathways by which mammalian cells are able to detect and …
mechanisms of oxygen sensing pathways by which mammalian cells are able to detect and …
[HTML][HTML] Epigenetics: new questions on the response to hypoxia
JI Perez-Perri, JM Acevedo, P Wappner - International journal of …, 2011 - mdpi.com
… Pablo Wappner … We thank Wappner lab members, especially Agostina Bertolin and Mariana
Melani … ; Perez-Perri, JI; Boccaccio, GL; Wappner, P. Drosophila genome-wide RNAi screen …
Melani … ; Perez-Perri, JI; Boccaccio, GL; Wappner, P. Drosophila genome-wide RNAi screen …
Control of the Hypoxic Response in Drosophila melanogaster by the Basic Helix-Loop-Helix PAS Protein Similar
…, M Muzzopappa, PJ Ratcliffe, P Wappner - … and cellular biology, 2002 - Taylor & Francis
In mammalian systems, the heterodimeric basic helix-loop-helix (bHLH)-PAS transcription
hypoxia-inducible factor (HIF) has emerged as the key regulator of responses to hypoxia. …
hypoxia-inducible factor (HIF) has emerged as the key regulator of responses to hypoxia. …
[HTML][HTML] Tracheal remodelling in response to hypoxia
L Centanin, TA Gorr, P Wappner - Journal of Insect Physiology, 2010 - Elsevier
… We wish to thank all members of the Wappner's lab for discussions and help in the preparation
of this review. PW is a Howard Hughes Medical Institute International Research Scholar. …
of this review. PW is a Howard Hughes Medical Institute International Research Scholar. …
OGFOD1 catalyzes prolyl hydroxylation of RPS23 and is involved in translation control and stress granule formation
…, BM Kessler, P Wappner… - Proceedings of the …, 2014 - National Acad Sciences
… These observations differ from ours: in HeLa cells we did not observe an effect of OGFOD1
intervention on p–eIF2α either in unstressed cells or under similar conditions of arsenite …
intervention on p–eIF2α either in unstressed cells or under similar conditions of arsenite …
[PDF][PDF] Cell autonomy of HIF effects in Drosophila: tracheal cells sense hypoxia and induce terminal branch sprouting
… We wish to thank Markus Affolter, Benny Shilo, Mark Krasnow, Jing Jin, Maria Leptin, and
the Bloomington Stock Center for fly lines and reagents; members of Wappner’s and Ceriani’s …
the Bloomington Stock Center for fly lines and reagents; members of Wappner’s and Ceriani’s …
The insulin-PI3K/TOR pathway induces a HIF-dependent transcriptional response in Drosophila by promoting nuclear localization of HIF-α/Sima
…, M Irisarri, S Oldham, P Wappner - Journal of cell …, 2005 - journals.biologists.com
… 2 ] to phosphatidylinositol (3,4,5)-trisphosphate [PtdIns(3,4,5)P 3 ] in a reaction antagonized
by the phosphatase PTEN. PtdIns(3,4,5)P 3 promotes recruitment to the plasma membrane …
by the phosphatase PTEN. PtdIns(3,4,5)P 3 promotes recruitment to the plasma membrane …
[PDF][PDF] The TIP60 complex is a conserved coactivator of HIF1A
… Left: volcano plot of log2 fold change against Àlog10 p value for all genes in normoxia versus
hypoxia is shown. Green circles, HIF1A-dependent hypoxia-inducible genes; purple circles…
hypoxia is shown. Green circles, HIF1A-dependent hypoxia-inducible genes; purple circles…
Cloning of hif-1α and hif-2α and mRNA expression pattern during development in zebrafish
…, L Centanin, M Antonelli, P Wappner… - Gene expression …, 2007 - Elsevier
… Both zebrafish HIF-α proteins displayed prolyl residues, presumably hydroxylated by the
oxygen sensor and required for ubiquitin-mediated degradation (P 402 , and P 564 , in human …
oxygen sensor and required for ubiquitin-mediated degradation (P 402 , and P 564 , in human …
Reversion of lethality and growth defects in Fatiga oxygen‐sensor mutant flies by loss of Hypoxia‐Inducible Factor‐α/Sima
L Centanin, PJ Ratcliffe, P Wappner - EMBO reports, 2005 - embopress.org
… We also described a lethal P-element insertional mutation (l(3)02255) in the Drosophila PHD
gene (CG1114 in FlyBase) that fails to downregulate Sima protein in normoxia, thus driving …
gene (CG1114 in FlyBase) that fails to downregulate Sima protein in normoxia, thus driving …