Over the last 20 years, the essential mechanisms of development have become clearer,
mainly because modern molecular genetics has transformed traditional embryology. The …

… In the ectoderm, segments are AP pairs of compartments and we call the alternative PA pair,
where P is the anteriorly located one and A the posteriorly located one, a parasegment (Fig. …

Over many years evidence has accumulated that plants and animals can regulate growth
with reference to overall size rather than cell number. Thus, organs and organisms grow until …

This book presents an up-to-date but simplified picture of fly development. The developmental
processes of Drosophila are followed from the formation of the egg, through the …

… Lawrence … Lawrence: He has edited the journal Development since 1976, served on the
editorial board of Cell and EMBO J., authored many papers and reviewed many more … Lawrence …

Our results demonstrate that the normal function of the engrailed (en) gene is required for
the maintenance of the straight boundary between cells of the anterior and posterior …

… The mutation affects the wing imaginal discs so that in some discs, but not others, the cells
that should make a wing make an extra notum instead (Morata and Lawrence, 1977b). The …

FHC Crick and PA Lawrence divide in all about 10 or 11 times (on average) to give a total of
some 50,000 cells (5). Shortly after puparium formation cell division of the disc stops. The …

Results Raising Antibodies to the wingless Protein As an immunogen to raise wingless-specific
antibodies, we made fusion proteins of the bacterial rrpE protein and different parts of the …

Most of the thoracic and abdominal segments of Drosophila are specified early in embryogenesis
by the overlapping activities of the hunchback (hb), Kriippel, knirps, and giant gap …