User profiles for P. E. Barran

Perdita Barran

Professor Mass Spectrometry University of Manchester
Verified email at manchester.ac.uk
Cited by 9122

How useful is ion mobility mass spectrometry for structural biology? The relationship between protein crystal structures and their collision cross sections in the gas …

E Jurneczko, PE Barran - Analyst, 2011 - pubs.rsc.org
… Her current research in the Barran group investigates the effects of different drift gases on
protein ions using IM-MS, as well as exploring the use of IM-MS to examine intrinsic disorder in …

Mass spectrometry based tools to investigate protein–ligand interactions for drug discovery

…, RA Garlish, RJ Taylor, PE Barran - Chemical Society …, 2012 - pubs.rsc.org
… Lippens and PE Barran, A comparison of mass spectrometry based hydrogen deuterium
exchange methods for probing the cyclophilin A cyclosporin complex, J. Chromatogr., A, 2010, …

Structure–activity relationships in β‐defensin peptides

K Taylor, PE Barran, JR Dorin - Peptide Science, 2008 - Wiley Online Library
The β‐defensins comprise a large family of small cationic antimicrobial peptides widely
distributed in plants, mammals and insects. These cysteine rich peptides display multifunctional …

[HTML][HTML] Identification and proteomic profiling of exosomes in human cerebrospinal fluid

JM Street, PE Barran, CL Mackay, S Weidt… - Journal of translational …, 2012 - Springer
Background Exosomes are released from multiple cell types, contain protein and RNA species,
and have been exploited as a novel reservoir for disease biomarker discovery. They can …

Luminescent, enantiopure, phenylatopyridine iridium-based coordination capsules

…, SJ Coles, J Michel, AC Jones, PE Barran… - Journal of the …, 2012 - ACS Publications
The first molecular capsule based on an [Ir(ppy) 2 ] + unit (ppy = 2-phenylatopyridine) has
been prepared. Following the development of a method to resolve rac-[(Ir(ppy) 2 Cl) 2 ] into its …

Applications of ion mobility mass spectrometry for high throughput, high resolution glycan analysis

…, R Upton, LG Migas, CE Eyers, PE Barran… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Background Diverse varieties of often heterogeneous glycans are ubiquitous in nature. They
play critical roles in recognition events, act as energy stores and provide structural stability …

Active‐metal template synthesis of a molecular trefoil knot

PE Barran, HL Cole, SM Goldup… - Angewandte Chemie …, 2011 - Wiley Online Library
Although many different approaches to catenanes and rotaxanes have been introduced,[1]
few strategies have been successfully developed for the synthesis of molecular knots.[2] …

Advancing solutions to the carbohydrate sequencing challenge

CJ Gray, LG Migas, PE Barran, K Pagel… - Journal of the …, 2019 - ACS Publications
Carbohydrates possess a variety of distinct features with stereochemistry playing a particularly
important role in distinguishing their structure and function. Monosaccharide building …

Dynamics of intact immunoglobulin G explored by drift‐tube ion‐mobility mass spectrometry and molecular modeling

…, RJ Taylor, AJ Henry, PE Barran - Angewandte Chemie …, 2014 - Wiley Online Library
Collision cross‐sections (CCS) of immunoglobulins G1 and G4 have been determined using
linear drift‐tube ion‐mobility mass spectrometry. Intact antibodies and Fc‐hinge fragments …

A mass-spectrometry-based framework to define the extent of disorder in proteins

…, JMD Kalapothakis, CE MacPhee, PE Barran - Analytical …, 2014 - ACS Publications
… , Medical College of Wisconsin; Ted Hupp, University of Edinburgh; Tilo Kunath, University
of Edinburgh; Galina Selivanova, The Karolinska Institute; and UCB Pharma and all Barran