User profiles for P. H. O’Farrell
Patrick H O'FarrellProfessor, Department of Biochemistry, UCSF Verified email at cgl.ucsf.edu Cited by 50648 |
Comparative genomics of the eukaryotes
A comparative analysis of the genomes ofDrosophila melanogaster, Caenorhabditis
elegans, and Saccharomyces cerevisiae—and the proteins they are predicted to encode—was …
elegans, and Saccharomyces cerevisiae—and the proteins they are predicted to encode—was …
High resolution two-dimensional electrophoresis of basic as well as acidic proteins
PZ O'Farrell, HM Goodman, PH O'Farrell - Cell, 1977 - cell.com
… pH 5-7 and pH 3-10 mixture was not successful since in the presence of urea, the basic
region of the pH … of the pH gradient, the few moderately basic proteins which entered the gel …
region of the pH … of the pH gradient, the few moderately basic proteins which entered the gel …
[HTML][HTML] High resolution two-dimensional electrophoresis of proteins.
PH O'Farrell - Journal of biological chemistry, 1975 - Elsevier
… gradient because the high concentration of urea causes large changes in pH as well as the
… the pH gradient does not extend significantly above pH 7. Extension of this pH gradient to pH …
… the pH gradient does not extend significantly above pH 7. Extension of this pH gradient to pH …
[PDF][PDF] Embryonic cleavage cycles: how is a mouse like a fly?
The evolutionary advent of uterine support of embryonic growth in mammals is relatively
recent. Nonetheless, striking differences in the earliest steps of embryogenesis make it difficult …
recent. Nonetheless, striking differences in the earliest steps of embryogenesis make it difficult …
Two-tiered regulation of spatially patterned engrailed gene expression during Drosophila embryogenesis
…, J Heemskerk-Jongens, JA Kassis, PH O'Farrell - Nature, 1988 - nature.com
… , the major transcription unit with start site (O) and presumed translation start site (AUG) and
the … cannot be due to leakiness of the ptc allele because the same delay is o):,served in ptc1 …
the … cannot be due to leakiness of the ptc allele because the same delay is o):,served in ptc1 …
Genetic control of cell division patterns in the Drosophila embryo
BA Edgar, PH O'Farrell - Cell, 1989 - cell.com
… We injected these embryos with 50 mM BrdU (pH 9) during G2 of cycle 14, allowed … and
O’Farrell(i989). DNA preparations for Southern blots were carried out as in Lehner and O’Farrell (…
O’Farrell(i989). DNA preparations for Southern blots were carried out as in Lehner and O’Farrell (…
The endocytic pathway mediates cell entry of dsRNA to induce RNAi silencing
…, A Hekele, A Gillis, E Foley, PH O'Farrell… - Nature cell …, 2006 - nature.com
… and lysed in hypotonic buffer (10 mM HEPES at pH 7.3, 6 mM β-mercaptoethanol, complete
… We are grateful to members of the Andino and O'Farrell labs for support and discussions; G. …
… We are grateful to members of the Andino and O'Farrell labs for support and discussions; G. …
The sequence specificity of homeodomain-DNA interaction
C Desplan, J Theis, PH O'Farrell - Cell, 1988 - cell.com
… We are grateful to the people in the O’Farrell lab for their support. In particular, we thank
Steve DiNardo, Jim Jaynes, Jill Jongens, Bill Kalionis, Delia Lakich, Christian Lehner, and John …
Steve DiNardo, Jim Jaynes, Jill Jongens, Bill Kalionis, Delia Lakich, Christian Lehner, and John …
The three postblastoderm cell cycles of Drosophila embryogenesis are regulated in G2 by string
BA Edgar, PH O'Farrell - Cell, 1990 - cell.com
The string (sfg) locus of Drosophila encodes a factor that is thought to trigger mitosis by
activating the p34CdC2 protein kinase. stg is required for mitosis early in development and is …
activating the p34CdC2 protein kinase. stg is required for mitosis early in development and is …
Progression of the cell cycle through mitosis leads to abortion of nascent transcripts
AW Shermoen, PH O'Farrell - Cell, 1991 - cell.com
… Furthermore, the completed Ubx transcript has a very short lifetime (AW Shermoen and
PH O'Farrell, unpublished data), so that the majority of the life span of a Ubx transcript is …
PH O'Farrell, unpublished data), so that the majority of the life span of a Ubx transcript is …