Neuromedin U (NmU) is a structurally highly conserved neuropeptide. It is ubiquitously
distributed, with highest levels found in the gastrointestinal tract and pituitary. Originally isolated …

10.7554/eLife.31274.001 In cycling human endometrium, menstruation is followed by rapid
estrogen-dependent growth. Upon ovulation, progesterone and rising cellular cAMP levels …

Menstruation drives cyclic activation of endometrial progenitor cells, tissue regeneration, and
maturation of stromal cells, which differentiate into specialized decidual cells prior to and …

During the implantation window, the endometrium becomes poised to transition to a
pregnant state, a process driven by differentiation of stromal cells into decidual cells (DC). …

Decidualizing endometrial stromal cells (EnSC) critically determine the maternal response
to an implanting conceptus, triggering either menstruation‐like disposal of low‐fitness …

The human luteinising hormone choriogonadotropin receptor (LHCGR) is a G-protein coupled
receptor activated by both human chorionic gonadotropin (hCG) and luteinizing hormone (…

Pregnancy depends on the wholesale transformation of the endometrium, a process driven
by differentiation of endometrial stromal cells (EnSC) into specialist decidual cells. Upon …

Background Recurrent pregnancy loss (RPL) is associated with the loss of endometrial
mesenchymal stem-like progenitor cells (eMSC). DPP4 inhibitors may increase homing and …

The neuropeptide neuromedin U (NmU) shows considerable structural conservation across
species. Within the body, it is widely distributed and in mammals has been implicated in …

Implantation requires coordinated interactions between the conceptus and surrounding
decidual cells, but the involvement of clock genes in this process is incompletely understood. …