User profiles for P. M. Beard

Philippa Beard

The Pirbright Institute
Verified email at pirbright.ac.uk
Cited by 2916

Do non-ruminant wildlife pose a risk of paratuberculosis to domestic livestock and vice versa in Scotland?

MJ Daniels, MR Hutchings, PM Beard… - Journal of wildlife …, 2003 - meridian.allenpress.com
… Histopathologic changes varied from mild to severe (Beard et al., 2001b). Following … with
few or no microscopic lesions (Beard et al., 2001b). The findings of Beard et al. (2001a) make it …

Paratuberculosis infection of nonruminant wildlife in Scotland

PM Beard, MJ Daniels, D Henderson… - Journal of clinical …, 2001 - Am Soc Microbiol
Recent reports of natural paratuberculosis (or Johne's disease) in rabbits, foxes, and stoats
has focused debate on the presence and importance of wildlife reservoirs in the …

[HTML][HTML] IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

…, J Taylor, IR Kelsall, AG Bowie, PM Beard… - Nature …, 2017 - nature.com
Many human cells can sense the presence of exogenous DNA during infection though the
cytosolic DNA receptor cyclic GMP-AMP synthase (cGAS), which produces the second …

Lumpy skin disease: a direct threat to Europe

PM Beard - The Veterinary Record, 2016 - search.proquest.com
In particular the role of vector transmission and the vectors involved is unclear.[...] the
effectiveness of quarantine zones and vector control as part of an eradication campaign cannot be …

Natural paratuberculosis infection in rabbits in Scotland

PM Beard, SM Rhind, D Buxton, MJ Daniels… - Journal of Comparative …, 2001 - Elsevier
Natural paratuberculosis infection of rabbits (Oryctolagus cuniculus) was recently diagnosed
in Scotland, and an investigation into the pathology of the disease in wild rabbits is reported …

Pleiotropic effects of extended blockade of CSF1R signaling in adult mice

…, S Raza, L Moffat, DJ Gow, PM Beard… - Journal of leukocyte …, 2014 - academic.oup.com
We investigated the role of CSF1R signaling in adult mice using prolonged treatment with
anti-CSF1R antibody. Mutation of the CSF1 gene in the op/op mouse produces numerous …

Elevation of CpG frequencies in influenza A genome attenuates pathogenicity but enhances host response to infection

…, MQ Nicol, AJ Highton, P Klenerman, PM Beard… - Elife, 2016 - elifesciences.org
10.7554/eLife.12735.001 Previously, we demonstrated that frequencies of CpG and UpA
dinucleotides profoundly influence the replication ability of echovirus 7 (Tulloch et al., 2014). …

[HTML][HTML] Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor

…, L Moffat, A Sehgal, BM Stutchfield, S Raza, PM Beard… - Molecular Therapy, 2014 - cell.com
We have produced an Fc conjugate of colony-stimulating factor (CSF) 1 with an improved
circulating half-life. CSF1-Fc retained its macrophage growth-promoting activity, and did not …

[HTML][HTML] Risk factors for outbreaks of lumpy skin disease and the economic impact in cattle farms of Nakuru County, Kenya

SK Kiplagat, PM Kitala, JO Onono, PM Beard… - Frontiers in veterinary …, 2020 - frontiersin.org
Lumpy Skin Disease (LSD) is an emerging disease of cattle that causes substantial economic
loss to affected regions. However, factors favouring transmission under field conditions …

A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong

…, A Law, S Lycett, C Batten, PM Beard - Transboundary and …, 2022 - Wiley Online Library
Beard are the joint senior authors. … Final sequencing pools were loaded at 12 pM
concentration onto an Illumina MiSeq 300 cycle sequencing run with a 1% PhiX spike-in (Illumina). …