The olfactory system gives us an awareness of our immediate environment by allowing us
to detect airborne stimuli. The components necessary for detection of these odorants are …

Neurons are highly specialized cells of the nervous system that receive, process and
transmit electrical signals critical for normal brain function. Here, we review the intricate …

An organism's awareness of its surroundings is dependent on sensory function. As antennas
to our external environment, cilia are involved in fundamental biological processes such as …

The biogenesis, maintenance and function of primary cilia are controlled through intraflagellar
transport (IFT) driven by two kinesin-2 family members, the heterotrimeric KIF3A/KIF3B/…

Nonmotile cilia on olfactory sensory neurons (OSNs) compartmentalize signaling molecules,
including odorant receptors and cyclic nucleotide-gated (CNG) channels, allowing for …

Cilia dysfunction underlies a class of human diseases with variable penetrance in different
organ systems. Across eukaryotes, intraflagellar transport (IFT) facilitates cilia biogenesis and …

Axon initial segments (AISs) and nodes of Ranvier are sites of clustering of voltage-gated
sodium channels (VGSCs) in nervous systems of jawed vertebrates that facilitate fast long-…

Cilia regulate diverse functions such as motility, fluid balance, and sensory perception. The
cilia of olfactory sensory neurons (OSNs) compartmentalize the signaling proteins necessary …

Cilia are evolutionarily conserved microtubule-based organelles that are crucial for diverse
biological functions, including motility, cell signaling and sensory perception 1 . In humans, …

GABA A -receptor-based interneuron circuitry is essential for higher order function of the
human nervous system and is implicated in schizophrenia, depression, anxiety disorders, and …