Data-driven prediction of drug effects and interactions

NP Tatonetti, PP Ye, R Daneshjou… - Science translational …, 2012 - science.org
Adverse drug events remain a leading cause of morbidity and mortality around the world.
Many adverse events are not detected during clinical trials before a drug receives approval for …

Cutting edge: TLR2 is a functional receptor for acute-phase serum amyloid A

N Cheng, R He, J Tian, PP Ye, RD Ye - The Journal of Immunology, 2008 - journals.aai.org
Induced secretion of acute-phase serum amyloid A (SAA) is a host response to danger signals
and a clinical indication of inflammation. The biological functions of SAA in inflammation …

Frequency dependence of ultrasound neurostimulation in the mouse brain

PP Ye, JR Brown, KB Pauly - Ultrasound in medicine & biology, 2016 - Elsevier
… Patrick Ye has been supported by the Bruce E. and Doris A. Nelson Bioengineering
Fellowship and the Bruce and Elizabeth Dunlevie Fellowship (Stanford Interdisciplinary Graduate …

[HTML][HTML] Epigallocatechin gallate protects against oxidative stress-induced mitochondria-dependent apoptosis in human lens epithelial cells

K Yao, PP Ye, L Zhang, J Tan, XJ Tang… - Molecular vision, 2008 - ncbi.nlm.nih.gov
Purpose Oxidative stress has long been recognized as an important mediator of apoptosis
in lens epithelial cells and also plays an important role in the pathogenesis of cataracts.(-)-…

Elimination of peripheral auditory pathway activation does not affect motor responses from ultrasound neuromodulation

M Mohammadjavadi, PP Ye, A Xia, J Brown, G Popelka… - Brain stimulation, 2019 - Elsevier
Background Recent studies in a variety of animal models including rodents, monkeys, and
humans suggest that transcranial focused ultrasound (tFUS) has considerable promise for non…

[HTML][HTML] Electromagnetic noise inhibits radiofrequency radiation-induced DNA damage and reactive oxygen species increase in human lens epithelial cells

K Yao, W Wu, KJ Wang, S Ni, PP Ye, YB Yu, J Ye… - Molecular …, 2008 - ncbi.nlm.nih.gov
Purpose The goal of this study was to investigate whether superposing of electromagnetic
noise could block or attenuate DNA damage and intracellular reactive oxygen species (ROS) …

Involvement of PI3K/Akt Pathway in TGF-β2-Mediated Epithelial Mesenchymal Transition in Human Lens Epithelial Cells

K Yao, PP Ye, J Tan, XJ Tang, XC Shen Tu - Ophthalmic research, 2008 - karger.com
Background: Epithelial mesenchymal transition (EMT) of postoperative remnants of lens
epithelial cells (LECs) can lead to posterior capsule opacification. This study was designed to …

[HTML][HTML] The flavonoid, fisetin, inhibits UV radiation-induced oxidative stress and the activation of NF-кB and MAPK signaling in human lens epithelial cells

K Yao, L Zhang, YD Zhang, PP Ye, N Zhu - Molecular Vision, 2008 - ncbi.nlm.nih.gov
Purpose Ultraviolet (UV) radiation-induced oxidative stress plays a significant role in the
progression of cataracts. This study investigated the photoprotective effect of fisetin on UV …

Immunoreactivity of Stat5 phosphorylated on tyrosine as a cell‐based measure of Bcr/Abl kinase activity

…, RM Sramkoski, PS Frisa, PP Ye… - Cytometry Part …, 2003 - Wiley Online Library
Background Stat5 1 (Signal Transducer and Activator of Transcription 5) is normally
phosphorylated and activated by Janus kinases. In cells transformed with BCR/ABL, Stat5 is …

Observation of a Near-Threshold Enhancement in the Mass Spectrum from Radiative Decays

…, GA Yang, HX Yang, J Yang, SD Yang, MH Ye - Physical review …, 2003 - APS
… of pp pairs from radiative J= ! pp decays. No similar structure is seen in J= ! 0pp decays. …
We select events that have fit confidence level CLpp > 0:05 and reject events that have CL…