… The BNP measurement could contribute to the timing of pulmonary valve replacement in
TOF patients with PR. However, the studies that have been conducted so far cannot be used to …

Tobacco and alcohol use are leading causes of mortality that influence risk for many complex
diseases and disorders 1 . They are heritable 2 , 3 and etiologically related 4 , 5 behaviors …

Intelligence is highly heritable 1 and a major determinant of human health and well-being 2
. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …

Insomnia is the second most prevalent mental disorder, with no sufficient treatment available.
Despite substantial heritability, insight into the associated genes and neurobiological …

The regional distribution of white matter (WM) abnormalities in schizophrenia remains poorly
understood, and reported disease effects on the brain vary widely between studies. In an …

Neuroticism is an important risk factor for psychiatric traits, including depression 1 , anxiety 2
, 3 , and schizophrenia 4 , 5 – 6 . At the time of analysis, previous genome-wide association …

Intelligence is associated with important economic and health-related life outcomes 1.
Despite intelligence having substantial heritability 2 (0.54) and a confirmed polygenic nature, …

Insomnia is a heritable, highly prevalent sleep disorder for which no sufficient treatment
currently exists. Previous genome-wide association studies with up to 1.3 million subjects …

Human brain structure changes throughout the lifespan. Altered brain growth or rates of
decline are implicated in a vast range of psychiatric, developmental and neurodegenerative …

The use of spoken and written language is a fundamental human capacity. Individual
differences in reading- and language-related skills are influenced by genetic variation, with twin-…