Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms

…, M Safari, S Sangwan, K Schaefer, PV Thomas… - Science, 2020 - science.org
… Tom70 is one of the major import receptors in the translocase of the outer membrane (TOM)
complex that recognizes and mediates the translocation of mitochondrial preproteins from …

[HTML][HTML] Trimeric HIV-1-Env structures define glycan shields from clades A, B, and G

…, T Lemmin, GY Chuang, A Druz, R Kong, PV Thomas… - Cell, 2016 - cell.com
The HIV-1-envelope (Env) trimer is covered by a glycan shield of ∼90 N-linked oligosaccharides,
which comprises roughly half its mass and is a key component of HIV evasion from …

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

…, GBE Stewart-Jones, J Stuckey, PV Thomas… - Nature structural & …, 2015 - nature.com
As the sole viral antigen on the HIV-1–virion surface, trimeric Env is a focus of vaccine efforts.
Here we present the structure of the ligand-free HIV-1–Env trimer, fix its conformation and …

A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates

…, C Subra, RE Chen, PV Thomas… - Science translational …, 2021 - science.org
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants
stresses the continued need for next-generation vaccines that confer broad protection …

[HTML][HTML] Vaccine-induced antibodies that neutralize group 1 and group 2 influenza A viruses

MG Joyce, AK Wheatley, PV Thomas, GY Chuang… - Cell, 2016 - cell.com
Antibodies capable of neutralizing divergent influenza A viruses could form the basis of a
universal vaccine. Here, from subjects enrolled in an H5N1 DNA/MIV-prime-boost influenza …

[HTML][HTML] Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

…, C Chrysostomou, KH Hoi, Y Tsybovsky, PV Thomas… - Nature medicine, 2016 - nature.com
Molecular understanding of serological immunity to influenza has been confounded by the
complexity of the polyclonal antibody response in humans. Here we used high-resolution …

[PDF][PDF] SARS-CoV-2 ferritin nanoparticle vaccines elicit broad SARS coronavirus immunogenicity

…, WH Chen, RS Sankhala, A Hajduczki, PV Thomas… - Cell reports, 2021 - cell.com
The need for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) next-generation
vaccines has been highlighted by the rise of variants of concern (VoCs) and the long-term …

Structural basis of mitochondrial receptor binding and constriction by DRP1

R Kalia, RYR Wang, A Yusuf, PV Thomas, DA Agard… - Nature, 2018 - nature.com
Mitochondrial inheritance, genome maintenance and metabolic adaptation depend on
organelle fission by dynamin-related protein 1 (DRP1) and its mitochondrial receptors. DRP1 …

Affective and cognitive factors related to mathematics achievement

JL Higbee, PV Thomas - Journal of Developmental Education, 1999 - search.proquest.com
[...] there were no significant relationships between students' grades in their first mathematics
or statistics core curriculum course and any of the other variables included in this research. …

Effect of RF power and sputtering pressure on the structural and optical properties of TiO2 thin films prepared by RF magnetron sputtering

…, GP Daniel, K Joy, V Ramakrishnan, PV Thomas - Applied Surface …, 2011 - Elsevier
TiO 2 thin films were deposited onto quartz substrates by RF magnetron sputtering. The
samples deposited at various RF powers and sputtering pressures and post annealed at 873K, …