Digital pathology and image analysis in tissue biomarker research

PW Hamilton, P Bankhead, Y Wang, R Hutchinson… - Methods, 2014 - Elsevier
Digital pathology and the adoption of image analysis have grown rapidly in the last few years.
This is largely due to the implementation of whole slide scanning, advances in software …

Non-invasive in vivo imaging in small animal research

V Koo, PW Hamilton… - Analytical Cellular …, 2006 - content.iospress.com
Non-invasive real time in vivo molecular imaging in small animal models has become the
essential bridge between in vitro data and their translation into clinical applications. The …

Virtual microscopy and digital pathology in training and education

PW Hamilton, Y Wang, SJ McCullough - Apmis, 2012 - Wiley Online Library
Traditionally, education and training in pathology has been delivered using textbooks, glass
slides and conventional microscopy. Over the last two decades, the number of web‐based …

[HTML][HTML] QuPath: Open source software for digital pathology image analysis

…, JA James, M Salto-Tellez, PW Hamilton - Scientific reports, 2017 - nature.com
QuPath is new bioimage analysis software designed to meet the growing need for a user-friendly,
extensible, open-source solution for digital pathology and whole slide image analysis. …

The use of morphological characteristics and texture analysis in the identification of tissue composition in prostatic neoplasia

…, NH Anderson, PH Bartels, R Montironi, PW Hamilton - Human pathology, 2004 - Elsevier
Quantitative examination of prostate histology offers clues in the diagnostic classification of
lesions and in the prediction of response to treatment and prognosis. To facilitate the …

An automated machine vision system for the histological grading of cervical intraepithelial neoplasia (CIN)

…, D Thompson, PH Bartels, PW Hamilton - The Journal of …, 2000 - Wiley Online Library
The histological grading of cervical intraepithelial neoplasia (CIN) remains subjective, resulting
in inter‐ and intra‐observer variation and poor reproducibility in the grading of cervical …

Challenging the cancer molecular stratification dogma: intratumoral heterogeneity undermines consensus molecular subtypes and potential diagnostic value in …

…, WL Allen, SS McDade, DJ Waugh, PW Hamilton… - Clinical Cancer …, 2016 - AACR
PW Hamilton is an employee of, holds ownership interest (including patents) in, and is a
consultant/advisory board member for PathXL Ltd. PG Johnston holds ownership interest (…

Inter‐and intra‐observer variation in the histopathological reporting of cervical squamous in traepithelial lesion susing a modified Bethesda grading system

…, MY Walsh, CM Thornton, PW Hamilton… - … Journal of Obstetrics …, 1998 - Wiley Online Library
Objective 1. To assess inter‐ and intra‐observer variation in the histopathological reporting
of cervicalcolposcopic biopsies using a histologic modification of the cytological Bethesda …

Automated location of dysplastic fields in colorectal histology using image texture analysis

PW Hamilton, PH Bartels, D Thompson… - The Journal of …, 1997 - Wiley Online Library
… Bartels PH, Thompson D, Bartels HG, Montironi R, Scarpelli M, Hamilton PW. Machine
vision-based histometry of premalignant and malignant prostatic lesions. Pathol Res Pract 1995; …

[HTML][HTML] Integrated tumor identification and automated scoring minimizes pathologist involvement and provides new insights to key biomarkers in breast cancer

…, S McQuaid, M Salto-Tellez, PW Hamilton - Laboratory …, 2018 - Elsevier
Digital image analysis (DIA) is becoming central to the quantitative evaluation of tissue
biomarkers for discovery, diagnosis and therapeutic selection for the delivery of precision …