Central serous chorioretinopathy

M Wang, IC Munch, PW Hasler, C Prünte… - Acta …, 2008 - Wiley Online Library
Central serous chorioretinopathy (CSC) is a disease of the retina characterized by serous
detachment of the neurosensory retina secondary to one or more focal lesions of the retinal …

[PDF][PDF] Cell types of the human retina and its organoids at single-cell resolution

…, A Szabo, MB Stadler, S Orgül, S Picelli, PW Hasler… - Cell, 2020 - cell.com
Human organoids recapitulating the cell-type diversity and function of their target organ are
valuable for basic and translational research. We developed light-sensitive human retinal …

Targeting neuronal and glial cell types with synthetic promoter AAVs in mice, non-human primates and humans

…, XL Fang, ZB Jin, D Goldblum, PW Hasler… - Nature …, 2019 - nature.com
Targeting genes to specific neuronal or glial cell types is valuable for both understanding
and repairing brain circuits. Adeno-associated viruses (AAVs) are frequently used for gene …

[HTML][HTML] Validation of automated artificial intelligence segmentation of optical coherence tomography images

…, I Leung, B Hörmann, P Kaiser, S Suter, PW Hasler… - PloS one, 2019 - journals.plos.org
… The manual annotation of the ground truth for the four eye compartments was conducted
by independent human graders using an individual and password protected online tool …

[HTML][HTML] Safety and feasibility of a novel sparse optical coherence tomography device for patient-delivered retina home monitoring

P Maloca, PW Hasler, D Barthelmes… - … vision science & …, 2018 - tvst.arvojournals.org
Purpose: To study a novel and fast optical coherence tomography (OCT) device for home-based
monitoring in age-related macular degeneration (AMD) in a small sample yielding …

[HTML][HTML] Unraveling the deep learning gearbox in optical coherence tomography image segmentation towards explainable artificial intelligence

…, HPN Scholl, TK Schnitzer, T Singer, PW Hasler… - Communications …, 2021 - nature.com
Abstract Machine learning has greatly facilitated the analysis of medical data, while the
internal operations usually remain intransparent. To better comprehend these opaque …

[HTML][HTML] High-performance virtual reality volume rendering of original optical coherence tomography point-cloud data enhanced with real-time ray casting

…, JER de Carvalho, T Heeren, PW Hasler… - … vision science & …, 2018 - jov.arvojournals.org
… Maloca P, Gyger C, Hasler PW. A pilot study to image the vascular network of small
melanocytic choroidal tumors with speckle noise-free 1050-nm swept source optical coherence …

Correlation between intraretinal changes in diabetic macular oedema seen in fluorescein angiography and optical coherence tomography

W Soliman, B Sander, PW Hasler… - Acta …, 2008 - Wiley Online Library
Purpose: To study the relationship between intraretinal optical coherence tomography (OCT)
and fluorescein angiography (FA) findings in eyes with diabetic macular oedema (DMO). …

Safety study of 38 503 intravitreal ranibizumab injections performed mainly by physicians in training and nurses in a hospital setting

PW Hasler, S Brandi Bloch, J Villumsen… - Acta …, 2015 - Wiley Online Library
Safety study of 38 503 intravitreal ranibizumab injections performed mainly by physicians in
training and nurses in a hospital setting - Hasler - 2015 - Acta Ophthalmologica - Wiley …

[HTML][HTML] Choroidal vascular reaction to hand-grip stress in subjects with vasospasm and its relevance in glaucoma

K Gugleta, S Orgül, PW Hasler… - … & visual science, 2003 - iovs.arvojournals.org
purpose. To assess the impact of vascular dysregulation on choroidal blood flow response to
the hand-grip test and the relevance of this response to glaucoma. methods. Eighty healthy …